The Belgian Institute of Public Health registered from 2000 to 2005 a yearly average of 6,790 hospital admissions for rotavirus gastroenteritis in children less than 5 years of age. Very efficacious rotavirus vaccines are available nowadays. The surveillance of hospitalisation due to rotavirus gastroenteritis is a good target for the follow-up of vaccine-related prevention. In a large regional Belgian hospital, rotavirus is associated with 12% to 21% of all hospitalisation days among children less than 2 years of age. The general implementation of rotavirus vaccination could dramatically reduce the hospitalisation of young children due to rotavirus gastroenteritis in developed countries.
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http://dx.doi.org/10.1007/s00431-007-0428-9 | DOI Listing |
Front Pediatr
January 2025
Yunnan Provincial Key Laboratory of Public Health and Biosafety & Institute for AIDS/STD Control and Prevention, Yunnan Center for Disease Control and Prevention, Kunming, Yunnan, China.
Background: Rotavirus (RV), norovirus (NoV), human enteric adenovirus (HAdV), human astrovirus (HAstV), and sapovirus (SaV) are important viral causes of acute gastroenteritis (AGE) in children. However, limited information is available regarding AGE in Yunnan, Southwest China.
Methods: To investigate the prevalence of group A rotavirus (RVA), norovirus genogroups I (GI) and II (GII), and HAdV, HAstV, and SaV in children aged <5 years hospitalized with AGE between 2020 and 2022.
Front Public Health
January 2025
Bavarian Health and Food Safety Authority (LGL), Munich, Germany.
[This corrects the article DOI: 10.3389/fpubh.2024.
View Article and Find Full Text PDFTissue Cell
December 2024
Department of Immunology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran. Electronic address:
Rotavirus is the most important cause of severe gastroenteritis in infants and children worldwide. This virus causes an increase in inflammatory responses by increasing cellular oxidative stress and the expression and activity of the transcription factor NF-κB and COX-2. As a result of NF-κB activation, the expression of inflammatory cytokines also increases.
View Article and Find Full Text PDFVaccine
January 2025
Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address:
Background: The underlying causes for lower rotavirus vaccine effectiveness (VE) in high-child-mortality settings are not well understood. Uganda introduced the human monovalent G1P[8] rotavirus vaccine (Rotarix) in June 2018. We determined the effectiveness of Rotarix against rotavirus diarrhea requiring hospital care among Ugandan children.
View Article and Find Full Text PDFBackground: Viral gastroenteritis is a significant global health concern. An effective, rapid, and easy-to-use diagnostic tool is essential for screening causative viruses.
Methods: Forty-eight samples, known to be infected with one of the following viruses: norovirus, group A rotavirus, astrovirus, adenovirus, and sapovirus determined by reverse transcription-PCR and nucleotide sequencing, were evaluated by the Fast Track Diagnostics (FTD) viral gastroenteritis assay.
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