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Childhood trauma and subclinical PTSD symptoms predict adverse effects and worse outcomes across two mindfulness-based programs for active depression.
PLoS One
January 2025
Department of Psychiatry and Human Behavior, Warren Alpert Medical School, Brown University, Providence, RI, United States of America.
Within mindfulness-based programs (MBPs), mixed results have been found for the role of childhood trauma as a moderator of depression outcomes. Furthermore, childhood trauma and PTSD symptoms have been identified as possible risk factors for the occurrence of meditation-related adverse effects (MRAE). The present research examined multiple forms of childhood trauma and PTSD symptoms as predictors of depression treatment outcomes and MRAEs.
View Article and Find Full Text PDFTailoring anaesthetic strategies for diabetes research: Acepromazine vs. medetomidine in Aachen minipigs.
PLoS One
January 2025
Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Pre-established anaesthetic protocols in animal models might unexpectedly interfere with the main outcome of scientific projects and therefore they need to account for the specific research goals. We aimed to optimize the anaesthetic protocol and animal handling strategies in a diabetes-related-study exemplifying how the anaesthetic approach must be adjusted for individual research targets. Aachen minipigs were used as a model to test long-lasting skin glucose sensors for diabetic human patients.
View Article and Find Full Text PDFDefense guard: strategies of plants in the fight against Cadmium stress.
Adv Biotechnol (Singap)
December 2024
State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Stress Biology, School of Agriculture and Biotechnology, Shenzhen Campus of Sun Yat-Sen University, Sun Yat-Sen University, Shenzhen City, 518107, China.
Soil Cadmium (Cd) contamination is a worldwide problem with negative impacts on human health. Cultivating the Cd-Pollution Safety Cultivar (Cd-PSC) with lower Cd accumulation in edible parts of plants is an environmentally friendly approach to ensure food security with wide application prospects. Specialized mechanisms have been addressed for Cd accumulation in crops.
View Article and Find Full Text PDFStressors and Support Experienced by Active Duty U.S. Navy Sailors at Sea.
Mil Med
January 2025
San Diego State University School of Public Health, San Diego, CA 92182, USA.
Introduction: High occupational stress is generally associated with poorer mental health and reduced performance in military personnel, whereas access to support resources is associated with positive outcomes. However, little research has examined the unique stressors and supports experienced by sailors on ships while underway at sea. The objectives of this study were to (1) identify sailors' underway stressors and supports and (2) examine how these differ as a function of demographic and operational factors.
View Article and Find Full Text PDFEvaluation of LMG S-31876 for immunomodulation and stress: a double-blind, placebo-controlled clinical trial.
Front Nutr
January 2025
Process Design and Engineering Cell, CSIR-Central Salt and Marine Chemicals Research Institute, Bhavnagar, Gujarat, India.
Objective: The study aimed to analyze the safety and effectiveness of the ProBC Plus ( LMG S-31876) supplement across various health parameters, including stress levels, immunoglobulin levels, biochemical parameters, and vital signs.
Methods: A randomized, double-blind, placebo-controlled clinical trial study was conducted involving 50 subjects diagnosed with ailments related to immune system dysfunction and stress related disorders. Patients were treated with ProBC Plus (2 billion colony-forming units [CFU]) along with a placebo capsule administered once daily for a period of 8 weeks.
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