[Case-matched study of pcbs toxiciy effects to women and children case in the areas which disused transformers were dismantled].

Objective: To Study the health-related effects of PCBs pollution to women and children living near the dismantling factories of disused transformers.

Methods: 49 couples which include a pair of preschool child(8 - 10 years old) and his/her mother were matched as the objects from the central junior school of F neighborhood where the study was progressing. Fasting Venous blood was collected from the objects, in which the content of PCBs (including 13 isomers) was determined by ultrasonic trace analyses methods as well as blood and urine were subjected to biochemical test while investigation by questionnaire and physical examination were also required.

Results: The mean content(G) of PCBs is 176ng/g lipid in the venous blood of the women and 192 ng/g lipid in that of the children. There are 6% of the females found blood pressure abnormality in the physical examination, while 28% of those were found urinary routine abnormality and 4% lymph node tumefaction. Among the children, 82% of them were suffered from caries, 6% were found lymph node tumefaction and 16% urinary abnormality.

Conclusions: Both the results of the blood and urine biochemical analyses as well as the physical examination indicated the prevalent abnormal status of the women and children in the area. The accumulating concentration of the PCBs in blood suggested that the dismantling of the disused transformers had resulted in a noticeable negative effect to the local environment.