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Brexpiprazole for a Patient with Ekbom Syndrome with Intolerable Side Effect of Aripiprazole.
Psychiatry Clin Psychopharmacol
September 2024
Department of Psychiatry, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Article Synopsis
- Ekbom's syndrome, or delusional parasitosis, is a rare psychiatric disorder characterized by a strong belief in having an infestation without hallucinations or major thought issues.
- It has two forms: primary, which features delusions and unusual sensations, and secondary, caused by an underlying health issue.
- A case study shows that atypical antipsychotics like aripiprazole and brexpiprazole can effectively treat primary Ekbom's syndrome, with brexpiprazole potentially causing fewer side effects like tremors.
From Psychiatric Care to Dermatologic Dilemmas: A Case Report of Risperidone-Induced Bullous Pemphigoid.
Cureus
September 2024
Psychiatry, All India Institute of Medical Sciences, Gorakhpur, Gorakhpur, IND.
Article Synopsis
- - The patient is a 64-year-old male with a long history of delusional disorder, first showing symptoms at age 34, which were managed successfully for years until a relapse occurred.
- - Initial treatment with amisulpride failed, and risperidone caused severe skin reactions leading to a diagnosis of bullous pemphigoid, prompting a switch to other medications.
- - The introduction of aripiprazole and melatonin resulted in improved management of both delusional symptoms and the skin condition, illustrating the importance of monitoring for drug-induced side effects in elderly patients on antipsychotics.
Unveiling the Burden of Drug-Induced Impulsivity: A Network Analysis of the FDA Adverse Event Reporting System.
Drug Saf
December 2024
Pharmacology Unit, Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.
Article Synopsis
- Impulsivity caused by dopaminergic drugs like pramipexole and aripiprazole can lead to serious behavioral addictions, affecting patients' social lives and overall quality of life.
- The study aimed to investigate the signs and secondary effects of this impulsivity, using comprehensive data analysis to identify key symptoms for potential intervention.
- Results indicate that a notable percentage of patients experience drug-induced impulsivity, with common issues including obsessive-compulsive disorder and economic problems, highlighting the need for better awareness and management in clinical settings.
Antipsychotic use in a large community sample of patients with delusional disorder.
Schizophr Res
September 2024
Department of Psychiatry, Fundación Jiménez Díaz University Hospital, Madrid, Spain; Department of Psychiatry, Rey Juan Carlos University Hospital, Móstoles, Spain; CIBERSAM (Centro de Investigación Biomédica en Red Salud Mental), Carlos III Institute of Health, Madrid, Spain; Department of Psychiatry, Madrid Autonomous University, Madrid, Spain; Department of Psychiatry, General Hospital of Villalba, Madrid, Spain; Department of Psychiatry, Infanta Elena University Hospital, Valdemoro, Spain; Department of Psychiatry, Centre Hospitalier Universitaire de Nîmes, Nimes, France; Department of Psychiatry, Health Research Institute Jimenez Diaz Foundation, Madrid, Spain.
Background: To examine clinical and sociodemographic differences between patients with delusional disorder; with and without diagnoses of an additional severe mental disorder (SMD) or cognitive impairment.
Methods: Population-based study including all individuals diagnosed with DD between 2005 and 2021 from a large catchment area in Madrid, Spain. Sociodemographic and clinical characteristics and the antipsychotic prescription patterns of the study population was described.
Efficacy of antipsychotics in delusional infestation.
J Eur Acad Dermatol Venereol
May 2024
Department of Dermatology, Barts Health NHS Trust, London, UK.
Background: Data remain scarce for the first-line antipsychotic choice in treating delusional infestation (DI).
Objectives: We evaluated the treatment responses associated with different antipsychotics in DI patients.
Methods: We undertook a multicentre, retrospective observational study using anonymised electronic patient records from two hospitals in the United Kingdom from 1 January 2011 to 1 January 2023.
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