The electrophilic cyclization of substituted propargylic aryl ethers by I2, ICl, and PhSeBr produces 3,4-disubstituted 2H-benzopyrans in excellent yields. This methodology results in vinylic halides or selenides under mild reaction conditions and tolerates a variety of functional groups, including methoxy, alcohol, aldehyde, and nitro groups.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527782 | PMC |
| http://dx.doi.org/10.1021/jo062234s | DOI Listing |
Publication Analysis
Top Keywords
34-disubstituted 2h-benzopyrans
8
electrophilic cyclization
8
synthesis 34-disubstituted
4
2h-benzopyrans c-c
4
c-c bond
4
bond formation
4
formation electrophilic
4
cyclization electrophilic
4
cyclization substituted
4
substituted propargylic
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!