A state-transition model of HIV disease was used to project the costs to Medicaid, Medicare, and AIDS Drug Assistance Programs of proposed Section 1115 Medicaid demonstration projects for the early treatment of HIV-infected patients in Georgia and Massachusetts. Neither demonstration project was projected to meet 5-year tests of no increase in Federal spending and in both States average patient costs to all payers were highest in the first year after enrollment. In assessing expanded health care access for patients with chronic diseases, government payers should consider overall budgetary effects and separately analyze costs for each year's enrollees to avoid creating incentives to cap enrollments.
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Resusc Plus
January 2025
Emergency Medical Services, Capital Region of Denmark, Ballerup, Denmark.
Unlabelled: Out-of-hospital cardiac arrest (OHCA) remains a critical health concern, where prompt access to automated external defibrillators (AEDs) significantly improves survival. This scoping review broadly investigates the feasibility and impact of dronedelivered AEDs for OHCA response.
Methods: PubMed, Cochrane, and Web of Science were searched from inception to August 6, 2024, with eligibility broadly including empirical data.
Rev Panam Salud Publica
January 2025
Instituto Nacional de Cardiologia Rio de Janeiro Brazil Instituto Nacional de Cardiologia, Rio de Janeiro, Brazil.
Objective: To provide an overview of hospital-based health technology assessment (HB-HTA) activities in Latin America and the Caribbean, including the technologies assessed, resources utilized, evaluation methods employed, and challenges encountered.
Methods: A scoping review focused on HB-HTA using frameworks from the Joanna Briggs Institute was conducted across databases and gray literature.
Results: Seventeen studies were identified, and another two documents were retrieved manually at a conference, totaling 19 files.
Nat Commun
January 2025
Department of Chemistry, University of Helsinki, Helsinki, Finland.
Secondary organic aerosols (SOAs) significantly impact Earth's climate and human health. Although the oxidation of volatile organic compounds (VOCs) has been recognized as the major contributor to the atmospheric SOA budget, the mechanisms by which this process produces SOA-forming highly oxygenated organic molecules (HOMs) remain unclear. A major challenge is navigating the complex chemical landscape of these transformations, which traditional hypothesis-driven methods fail to thoroughly investigate.
View Article and Find Full Text PDFBMJ Glob Health
January 2025
Department of Epidemiology, University of Washington School of Public Health, Seattle, Washington, USA.
Introduction: Oral pre-exposure prophylaxis (PrEP) is a priority intervention for scale-up in countries with high HIV prevalence. Policymakers must decide how to optimise PrEP allocation to maximise health benefits within limited budgets. We assessed the health and economic impact of PrEP scale-up among different subgroups and regions in western Kenya.
View Article and Find Full Text PDFEnviron Pollut
January 2025
State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China. Electronic address:
As a vital precursor of hydroxyl radicals (OH), atmospheric nitrous acid (HONO) plays a significant role in tropospheric chemistry and the production of secondary pollutants. However, knowledge of its sources remains insufficient. To comprehensively investigate the HONO chemistry in polluted cities and alleviate the O pollution, based on a comprehensive HONO-related field campaign in Zibo City, on the North China Plain, the parameterized formulas of additional HONO sources were validated in a box model (based on the default MCMv3.
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