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| http://dx.doi.org/10.1136/bjsm.2006.032987 | DOI Listing |
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Semi-mechanistic efficacy model for PARP + ATR inhibitors-application to rucaparib and talazoparib in combination with gartisertib in breast cancer PDXs.
Br J Cancer
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Physiomics PLC, Abingdon, UK.
Background: Promising cancer treatments, such as DDR inhibitors, are often challenged by the heterogeneity of responses in clinical trials. The present work aimed to build a computational framework to address those challenges.
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Highly deformable flapping membrane wings suppress the leading edge vortex in hover to perform better.
Proc Natl Acad Sci U S A
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École polytechnique fédérale de Lausanne, School of Engineering, Institute of Mechanical Engineering, Unsteady Flow Diagnostics Laboratory, Lausanne 1015, Switzerland.
Airborne insects generate a leading edge vortex when they flap their wings. This coherent vortex is a low-pressure region that enhances the lift of flapping wings compared to fixed wings. Insect wings are thin membranes strengthened by a system of veins that does not allow large wing deformations.
View Article and Find Full Text PDFThe efficacy of resveratrol supplementation on inflammation and oxidative stress in type-2 diabetes mellitus patients: randomized double-blind placebo meta-analysis.
Front Endocrinol (Lausanne)
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Department of Traditional Chinese Medicine, Zigong First People's Hospital, Zigong, Sichuan, China.
Background: The effects of resveratrol supplementation on inflammation and oxidative stress in patients with type 2 diabetes mellitus (T2DM) were controversial. A meta-analysis was performed to assess the changes in levels of inflammation and oxidative stress in patients with T2DM.
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Front Endocrinol (Lausanne)
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Huangjiang Hospital, Dongguan, Guangdong, China.
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Association between different insulin resistance indices and all-cause mortality in patients with diabetic kidney disease: a prospective cohort study.
Front Endocrinol (Lausanne)
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Department of Urology, Harbin Medical University Cancer Hospital, Harbin, China.
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