Diffraction tomography is a technique for imaging with acoustic fields in which parameter, such as reflective index, sound velocity, etc., can be mapped from scatter wave resulting from insonifying the object with a plane wave at a single temporal frequency. By solving the direct scattering problem, the scattered field can be presented in term of scattering parameters. Different inversion techniques can be applied to take advantage of the linearization process of the non-linear wave equation describing wave propagation in heterogeneous media under a limited class of scattering. Specifically, when the scattering effect is weak, one can invoke the Born or Rytov approximation and thus derive the generalized Fourier slice theorem to reconstruct the cross-section of the insonified object. Although diffraction tomography is a promising technology for medical application as it provides a quantitative ultrasonic image, its realization toward medical use is still far-to-go, and this may be due to the complexity of the hardware involved. In this research we investigate a potential use of diffraction tomography for medical application by using a delicate-designed ultrasonic computerized tomographic system. The contribution of the paper is that we have purposed to frequency synthesis method (FSM) that uses 3 frequency components of the Fourier transform of scattered filed, i.e. the center frequency and the -3 dB from center frequency of both side, to fill Fourier space for the generalized Fourier slice theory. The reconstructed ultrasonic image from such theory provides a very promising result.
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http://dx.doi.org/10.1109/IEMBS.2005.1616803 | DOI Listing |
Adv Healthc Mater
December 2024
Department of Mechanical Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA.
Astrocytes, integral components of the central nervous system, are increasingly recognized for their multifaceted roles beyond support cells. Despite their acknowledged importance, understanding the intricacies of astrocyte morphological dynamics remains limited. Our study marks the first exploration of astrocytes using optical diffraction tomography (ODT), establishing a label-free, quantitative method to observe morphological changes in astrocytes over a 7-day in-vitro period.
View Article and Find Full Text PDFSubcell Biochem
December 2024
School of Biomedical Sciences, The University of New South Wales, Sydney, NSW, Australia.
Electron microscopy (EM) techniques have been crucial for understanding the structure of biological specimens such as cells, tissues and macromolecular assemblies. Viruses and related viral assemblies are ideal targets for structural studies that help to define essential biological functions. Whereas conventional EM methods use chemical fixation, dehydration, and staining of the specimens, cryogenic electron microscopy (cryo-EM) preserves the native hydrated state.
View Article and Find Full Text PDFTissue Cell
December 2024
Stem Cells Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; Department of Natural Sciences, West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan. Electronic address:
Addressing mandibular defects poses a significant challenge in maxillofacial surgery. Recent advancements have led to the development of various biomimetic composite scaffolds aimed at facilitating mandibular defect reconstruction. This study aimed to assess the regenerative potential of a novel composite scaffold consisting of polylactic acid (PLA), hydroxyapatite nanoparticles (n-HA), gelatin, hesperidin, and human dental pulp stem cells (DPSCs) in a rat model of mandibular bone defect.
View Article and Find Full Text PDFInorg Chem
December 2024
Physical Institute, Karlsruhe Institut of Technology (KIT) Campus South, Wolfgang-Gaede-Str. 1, Karlsruhe 76131, Germany.
The dinuclear β-diketiminato complex [LClDy(μ-Cl)DyL(THF)] () (L = {2,6-PrCH-NC(Me)CHC(Me)N-2,6-PrCH}) was obtained by reaction of DyCl with KL in a molar ratio of 1:1 and used for the preparation of the mixed-ligand complex [LDy(μ-3,5-Cat)] () by salt metathesis reaction with 3,5-CatK (3,5-Cat -3,5-di--butyl-catecholate). Reactions of 3,5-CatNa with [LLnCl(THF)] (Ln = Dy, Y) ligated with the less bulky ligand L = {2,4,6-MeCH-NC(Me)CHC(Me)N-2,4,6-MeCH} afforded the mixed-ligand THF-containing complexes [LLn(μ-3,5-Cat)(THF)] (Ln = Dy (), Y ()). All new complexes were fully characterized, and the solid-state structures were determined by single-crystal X-ray diffraction.
View Article and Find Full Text PDFJ Xray Sci Technol
December 2024
Henan Key Laboratory of Imaging and Intelligent Processing, Information Engineering University, Zhengzhou, Henan, China.
Background: Coherent diffraction imaging (CDI) is an important lens-free imaging method. As a variant of CDI, ptychography enables the imaging of objects with arbitrary lateral sizes. However, traditional phase retrieval methods are time-consuming for ptychographic imaging of large-size objects, e.
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