AI Article Synopsis
- The study focuses on the importance of flow-sensors for managing biological samples in micro Total Analysis Systems (µTAS)
- The choice between hybrid mounting and monolithic fabrication depends on design variables, especially the compatibility of the sensor with the pump
- The research highlights a successful fabrication of a flow-sensor using the same soft-lithographic process as electroosmotic pumps, showing good performance and addressing issues related to material aging.
Article Abstract
The closed-loop management of biological samples in μTAS requires proper flow-sensors to be inserted in the hydraulic path. The optimal choice between hybrid mounting and monolithic fabrication depends on several design variables, one of which is the technological compatibility between the sensor and the pumping mechanism. Monolithic integration appears to be the eligible solution if both pumps and sensors can be fabricated with the same technological process. In this paper we show that it is actually possible to fabricate a flow-sensor, based on streaming potential detection, with the same soft-lithographic process used for the fabrication of electroosmotic pumps. The device has been fabricated in PDMS and experimentally tested, showing a good linearity. Finally, its time-varying response, related to the aging of the PDMS surface, is discussed.
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| http://dx.doi.org/10.1109/IEMBS.2005.1615614 | DOI Listing |
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