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| http://dx.doi.org/10.1002/anie.200604546 | DOI Listing |
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Observation of ultraviolet photothermoelectric bipolar impulse in gallium-based heterostructure nanowires.
Nat Commun
January 2025
Key Laboratory of Advanced Photonic and Electronic Materials, Key Laboratory of Optoelectronic Devices and Systems with Extreme Performances of MOE and School of Electronic Science and Engineering, Nanjing University, Nanjing, 210093, China.
The incorporation of thermal dynamics alongside conventional optoelectronic principles holds immense promise for advancing technology. Here, we introduce a GaON/GaN heterostructure-nanowire ultraviolet electrochemical cell of observing a photothermoelectric bipolar impulse characteristic. By leveraging the distinct thermoelectric properties of GaON/GaN, rapid generation of hot carriers establishes bidirectional instantaneous gradients in concentration and temperature within the nanoscale heterostructure via light on/off modulation.
View Article and Find Full Text PDFVisualization of Mechanical Force Regulation of Exosome Secretion Using High Time-Spatial Resolution Imaging.
Anal Chem
January 2025
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, Jilin, China.
Article Synopsis
- Exosomes are small vesicles that help cells communicate and are influenced by the tumor environment, with mechanical forces potentially enhancing their release.
- Researchers used advanced imaging techniques to study how mechanical forces affect exosome release in real time, observing that these forces lead to more exosome release through the fusion of multivesicular bodies with the cell membrane.
- They identified that changes in the actin structure of cells, triggered by mechanical forces, are key to this process, paving the way for new strategies to address disease-related exosomes.
A portable and sensitive DNA-based electrochemical sensor for detecting piconewton-scale cellular forces.
Anal Chim Acta
January 2025
Department of Chemistry, University of Massachusetts, Amherst, MA, 01003, USA; Molecular and Cellular Biology Program, University of Massachusetts, Amherst, MA, 01003, USA. Electronic address:
Article Synopsis
- Cell-generated forces play a crucial role in various cellular processes, and measuring these forces is essential for understanding cell behavior in contexts like migration and cancer development, although existing methods are often complex and require specialized skills.
- A new smartphone-based electrochemical sensor has been developed, utilizing a DNA-based force probe that can detect cellular forces, enabling the measurement of small forces generated by just a few cells, like HeLa cells, through enhanced electrochemical signals.
- This innovative sensor is portable, cost-effective, and user-friendly, making it a promising complementary tool to existing techniques for detecting cellular forces in biological research.
Transient Receptor Potential Channels in Vascular Mechanotransduction.
Am J Hypertens
November 2024
Department of Pharmacology and Physiology, University of Rochester Medical Center, Rochester, New York, USA.
Article Synopsis
- Transmural pressure and shear stress are key mechanical forces that influence the behavior of smooth muscle cells (SMCs) and endothelial cells (ECs) in the vascular wall.
- Specific TRP cation channels (like TRPC6, TRPM4, TRPV1, TRPV4, and TRPP1) play a crucial role in regulating calcium levels in these cells, helping to adjust blood vessel tone based on changes in pressure and flow.
- Although these TRP channels are involved in sensing mechanical changes, there's limited evidence of their direct mechanosensitivity, prompting investigations into the signaling pathways that activate them in response to vascular forces.
Force-Induced Ultraviolet C Luminescence of Pr-Doped SrPO for X-Ray Dosimetry.
Adv Mater
December 2024
College of Physics Science and Technology, Hebei University, Baoding, 071002, China.
Mechanoluminescent materials have broad application prospects in advanced displays, stress imaging, and anti-counterfeiting owing to their ability to convert mechanical stimuli into light. However, most previous studies have focused on the visible and near-infrared regions. Although natural ultraviolet C (UVC) light is nearly absent on the Earth's surface, it plays an important role in many fields.
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