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Differentiation of Parkinson's disease and progressive supranuclear palsy with magnetic resonance imaging: the first Brazilian experience. | LitMetric

Differentiation of Parkinson's disease and progressive supranuclear palsy with magnetic resonance imaging: the first Brazilian experience.

Parkinsonism Relat Disord

Department of Neurology, Universidade Federal de São Paulo, Rua Cabedelo, 265 São Paulo, SP, Brazil.

Published: October 2007

Background: The objective of this study is to differentiate PSP from Parkinson's disease through magnetic resonance imaging.

Methods: We included 14 consecutive patients with PD (9) or PSP (5). These measures included the third ventricle, midbrain diameter, quadrigeminal plate, brainstem volumetry, and interpeduncular angle.

Results: Patients with PSP presented enlargement of third ventricle (100% vs. 33%), lower midbrain diameter (mean 13.2 +/- 1.7 mm vs. 16.5 +/- 1.7 mm) and thinning of the quadrigeminal plate (mean 2.7 +/- 0.3 mm vs. 3.6 +/- 0.3 mm) in comparison with PD.

Conclusions: Characteristic findings on MRI may help to differentiate PD from PSP.

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Source
http://dx.doi.org/10.1016/j.parkreldis.2006.12.011DOI Listing

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