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This paper presents an automated, patient-specific method for the detection of epileptic seizure onsets from noninvasive EEG. We adopt a patient-specific approach to exploit the consistency of an individual patient's seizure and non-seizure EEG. Our method uses a wavelet decomposition to construct a feature vector that captures the morphology and spatial distribution of an EEG epoch, and then determines whether that vector is representative of a patient's seizure or non-seizure EEG using the support-vector machine classification algorithm. Our completely automated method was tested on non-invasive EEG from thirty-six pediatric subjects suffering from a variety of seizure types. It detected 131 of 139 seizure events within 8.0+/-3.2 seconds following electrographic onset, and declared 15 false-detections in 60 hours of clinical EEG. Our patient-specific method can be used to initiate delay-sensitive clinical procedures following seizure onset; for example, the injection of an imaging radiopharmaceutical or stimulation of the vagus nerve.
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http://dx.doi.org/10.1109/IEMBS.2004.1403183 | DOI Listing |
Neurobiol Dis
December 2024
Institute of Physiology I, Münster University, Münster, Germany. Electronic address:
Spike-wave-discharges (SWD) are the electrophysiological hallmark of absence epilepsy. SWD are generated in the thalamo-cortical network and a seizure onset zone was identified in the somatosensory cortex (S1). We have shown before that inhibition of the centromedian thalamic nucleus (CM) in GAERS rats resulted in a selective suppression of the spike component while rhythmic cortical 5-9 Hz oscillations remained present.
View Article and Find Full Text PDFEpilepsy Res
December 2024
Neurology dapartment, faculty of medicine, Cairo university, Egypt. Electronic address:
Introduction: Older patients with Late onset epilepsy (LOE) provide a special set of difficulties for both the treating doctors and the patients.
Objectives: To address the characteristics and treatment outcomes of LOE in a cohort of Egyptian population at a tertiary center and to assess factors affecting seizure freedom in this age group.
Methods: From December 1, 1995, to November 30, 2020, we analysed all patients with newly diagnosed epilepsy above the age of 50 at Cairo University's neurology department.
J Epilepsy Res
December 2024
Department of Neurology, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Absence status epilepticus may occur in persons diagnosed with idiopathic/genetic epilepsy as well as in adult and elderly patients. Despite being a rare phenomenon, pregnant women with no previous history of epileptic seizures may be presented with new onset status epilepticus. In this report, we describe the case of a 22-year-old pregnant female with no prior history of seizures.
View Article and Find Full Text PDFJ Epilepsy Res
December 2024
Department of Neurology, Erenkoy Mental Health and Neurological Diseases Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Background And Purpose: Alzheimer's disease (AD) and epileptic seizure are among the most common health problems in the elderly population. This study aimed to estimate the prevalence rate and predictors of seizures in sporadic AD patients.
Methods: The study was conducted by retrospectively for a period of 10 years examining the file records.
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