An ultrasensitive imumunodiagnostic readout method based on an electrochemical analysis is presented. Different high-quality quantum dot (QD) nanocrystals (ZnS, CdS, and PbS) are tagged to antibodies for the on-site voltammetric stripping measurements of multiple antigen targets. These encoding QD tracers with distinct redox potential yield highly sensitive and selective stripping peaks at -1.11 V (Zn), -0.67 V (Cd) and - 0.52 V (Pb) at the mercury-coated glassy carbon electrode (vs. Ag/AgCI reference). The position and size of these peaks reflect the identity and level of the corresponding antigen target. The analog peaks of the QDs were converted to a digital bio-barcode system for simple and rapid medical diagnostics.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1109/IEMBS.2004.1403110 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Advances in Heavy Metal Sensing: Utilizing Immobilized Chromogenic Reagents, Nanomaterials Perovskite and Nanonzymes.
Crit Rev Anal Chem
January 2025
Department of Chemistry, University of Delhi, New Delhi, India.
Heavy metal pollution is a major environmental and health problem due to the toxicity and persistence of metals such as lead, mercury, cadmium, and arsenic in water, soil, and air. Advances in sensor technology have significantly improved the detection and quantification of heavy metals, providing real-time monitoring and mitigation tools. This review explores recent developments in heavy metal detection, focusing on innovative uses of immobilized chromogenic reagents, nanomaterials, perovskites, and nanozymes.
View Article and Find Full Text PDFApplication of biomass carbon dots in food packaging.
Environ Sci Pollut Res Int
January 2025
College of Materials Science and Engineering, Nanjing Forestry University, Nanjing, 210037, China.
Since its discovery, carbon quantum dots (CDs) have been widely applied in cell imaging, drug delivery, biosensing, and photocatalysis due to their excellent water solubility, chemical stability, fluorescence stability biocompatibility, low toxicity, and preparation cost. However, the low fluorescence yield and poor surface structure limit the application of CDs. Heteroatom doping is considered an ideal method to improve CDs' optical and electrical properties.
View Article and Find Full Text PDFFe-Co-Fe prussian blue analogues loaded nitrogen doped carbon quantum dots for effective epinephrine detection.
Talanta
January 2025
The School of Material Science and Chemical Engineering, Harbin University of Science and Technology, Harbin, 150040, PR China.
Epinephrine (Ep) is an important neurotransmitter, which plays an important role in the nervous system and glycogen metabolism of living organisms. Hence, a novel NCQDs/FeCoFe-PBA composite with FeCoFe-Prussian blue analogues (PBA) as the core and nitrogen-doped carbon quantum dots (NCQDs) as the shell was constructed by a one-pot hydrothermal method, and it was used for the efficient detection of Ep. As a good electroactive material, NCQDs in the composite not only improved the weak conductivity of FeCoFe-PBA, but also limited the self-aggregation of FeCoFe-PBA, and formed a uniform shell on FeCoFe-PBA.
View Article and Find Full Text PDFToxic effects and mechanistic insights of cadmium telluride quantum dots on the homeostasis and regeneration in planarians.
J Hazard Mater
December 2024
College of Life Science, Henan Normal University, Xinxiang 453007, China. Electronic address:
The widespread application of quantum dots (QDs) in recent years has raised concerns about potential environmental and human health risks. Although the toxicity of cadmium telluride quantum dots (CdTe QDs) has been partially studied, their effects on stem cells, tissue regeneration, neurodevelopment, and neurobehavioral toxicity remain unclear. This study aimed to investigate the combined toxic effects and mechanisms of CdTe QDs on planarians at the individual, tissue, cellular, and molecular levels.
View Article and Find Full Text PDFAggregation-induced emission and absorption enhancement of mixed-valent rhenium oxide quantum dots by triethylamine: Implications for food safety monitoring.
J Hazard Mater
December 2024
Department of Chemistry, National Sun Yat-sen University, No. 70 Lienhai Rd., Kaohsiung 80424, Taiwan; Center for Nanoscience & Nanotechnology, National Sun Yat-sen University, No. 70 Lienhai Rd., Kaohsiung 80424, Taiwan; School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, No.100, Shiquan 1st Rd., Kaohsiung 80708, Taiwan. Electronic address:
Food freshness monitoring and volatile amine detection are key to food safety. In this study, we demonstrated the applicability of mixed-valence rhenium oxide quantum dots (MV-ReOQDs), synthesized via the hydrothermal reaction of α-cyclodextrin and rhenium ion precursors, in triethylamine (TEA) sensing. Spectroscopic correlation techniques showed that the developed MV-ReOQDs possessed mixed-valent rhenium, α-cyclodextrin as capped ligand, partially carbonized surface, and amorphous phase structure.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!