AI Article Synopsis

  • The study focuses on creating polyimide templates using microfabrication, which have high aspect ratio pores produced through deep plasma etching.
  • Various metals are then deposited into these pores, and after removing the template, metallic rods are released into solution for analysis.
  • The unique metal striping patterns on these particles, which vary in size, allow for optical identification and have been tested in a multiplexed DNA hybridization assay.

Article Abstract

Lithographically defined polyimide templates were prepared using microfabrication techniques. The templates consist of high aspect ratio pores that were formed by deep plasma etching. Different metals are electrodeposited into the pores, and then the template is removed to allow the metallic rods (particles) to be released into solution. The striping pattern of metals on the particles is used to optically identify the particles. Particles range in size from 0.6 mum in diameter by 7.7 mum in length to 4.2 mum by 27 mum in length. These particles have been evaluated in a multiplexed DNA hybridization assay.

Download full-text PDF

Source
http://dx.doi.org/10.1109/IEMBS.2004.1403752DOI Listing

Publication Analysis

Top Keywords

mum length
8
particles
5
microfabricated templates
4
templates electrodeposition
4
electrodeposition metallic
4
metallic barcodes
4
barcodes multiplexed
4
multiplexed bioassays
4
bioassays lithographically
4
lithographically defined
4

Similar Publications

Room-temperature and recyclable preparation of cellulose nanofibers using deep eutectic solvents for multifunctional sensor applications.

Int J Biol Macromol

January 2025

State Key Lab for Hubei New Textile Materials and Advanced Processing Technology, College of Materials Science & Engineering, College of Textile Science & Engineering, Wuhan Textile University, 430200 Wuhan, China. Electronic address:

Cellulose nanofibers (CNFs) have gained increasing attention due to their robust mechanical properties, favorable biocompatibility, and facile surface modification. However, green and recyclable CNF production remains challenging. Herein, a green, low-cost and room-temperature strategy was developed to exfoliate CNFs using deep eutectic solvents.

View Article and Find Full Text PDF

The ultrafine MoO powders were prepared by the combination of centrifugal spray drying and calcination in this work. The thermal decomposition behavior of the spherical precursor was studied. The phase constituents, morphologies, particle size, and specific surface areas of MoO powders were characterized at different temperatures.

View Article and Find Full Text PDF

Inorganic-organic hybrid nanoparticles with carbonate-triggered emission-colour-shift.

Dalton Trans

January 2025

Karlsruhe Institute of Technology (KIT), Institute for Inorganic Chemistry, Engesserstrasse 15, 76131 Karlsruhe, Germany.

(Eu[PTC])(Eu[TREN-1,2-HOPO]) inorganic-organic hybrid nanoparticles (IOH-NPs) contain Eu, tris[(1-hydroxy-2-oxo-1,2-dihydropyridine-6-carboxamido)ethyl]amine (TREN-1,2-HOPO) and perylene-3,4,9,10-tetracarboxylate (PTC). The IOH-NPs are prepared in water and exhibit a rod-type shape, with a length of 60 nm and a diameter of 5 nm. Particle size and chemical composition are examined by different methods (SEM, DLS, FT-IR, TG, C/H/N analysis).

View Article and Find Full Text PDF

Controlling Microparticle Aspect Ratio via Photolithography for Injectable Granular Hydrogel Formation and Cell Delivery.

ACS Biomater Sci Eng

January 2025

Weldon School of Biomedical Engineering, Purdue University, West Lafayette 47907-2050, Indiana, United States.

Granular hydrogels are injectable and inherently porous biomaterials assembled through the packing of microparticles. These particles typically have a symmetric and spherical shape. However, recent studies have shown that asymmetric particles with high aspect ratios, such as fibers and rods, can significantly improve the mechanics, structure, and cell-guidance ability of granular hydrogels.

View Article and Find Full Text PDF

The cellular interior is a spatially complex environment shaped by non-trivial stochastic and biophysical processes. Within this complexity, spatial organizational principles-also called spatial phenotypes-often emerge with functional implications. However, identifying and quantifying these phenotypes in the stochastic intracellular environment is challenging.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!