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Phylogenomic analyses unravel the tangled evolutionary history of Genisteae (Fabaceae).
Mol Phylogenet Evol
November 2024
Department of Integrative Biology, University of Texas at Austin, Austin, TX, USA.
Article Synopsis
- Genisteae is a tribe in the legume family Fabaceae known for producing quinolizidine alkaloids that help resist pests, but its generic relationships remain unclear due to a lack of modern studies.
- Previous research identified three main clades within Genisteae: Lupinus, Cytisus-Genista, and Argyrolobium, with ongoing debates about the classification of certain genera like Teline and Chamaecytisus.
- Recent phylogenomic analysis, using extensive data from 24 of the tribe's 25 genera, revealed four significant clades within Genisteae, clarified the placement of Teline and Sellocharis, and supported the transfer of the Argyrolobium group into Gen
Antifungal activity against Fusarium oxysporum of quinolizidines isolated from three controlled-growth Genisteae plants: structure-activity relationship implications.
Nat Prod Bioprospect
March 2023
Bioorganic Chemistry Laboratory, Facultad de Ciencias Básicas y Aplicadas, Universidad Militar Nueva Granada, 250247, Cajicá, Colombia.
The Genisteae tribe belongs to the Fabaceae family. The wide occurrence of secondary metabolites, explicitly highlighting the quinolizidine alkaloids (QAs), characterizes this tribe. In the present study, twenty QAs (1-20), including lupanine (1-7), sparteine (8-10), lupanine (11), cytisine and tetrahydrocytisine (12-17), and matrine (18-20)-type QAs were extracted and isolated from leaves of three species (i.
View Article and Find Full Text PDFA Comprehensive Review of the Pharmacological Properties and Bioactive Components of .
Molecules
February 2023
Laboratory of Human Pathologies Biology, Department of Biology, Faculty of Sciences, Mohammed V University in Rabat, Rabat 10106, Morocco.
L. (Boiss.) or L.
View Article and Find Full Text PDFIdentification of Anti-Proliferative Compounds from Seeds through Covariate-Based Integration of Chemical Fingerprints and Bioactivity Datasets.
Molecules
June 2022
Bioorganic Chemistry Laboratory, Universidad Militar Nueva Granada, Cajicá 250247, Colombia.
Genista monspessulana (L.) L.A.
View Article and Find Full Text PDFDetermination of Cytisine and N-Methylcytisine from Selected Plant Extracts by High-Performance Liquid Chromatography and Comparison of Their Cytotoxic Activity.
Toxins (Basel)
August 2020
Department of Experimental and Clinical Pharmacology, University of Rzeszów, Kopisto 2a, 35-959 Rzeszów, Poland.
Quinolizidine alkaloids exhibit various forms of biological activity. A lot of them were found in the family, including and . The aim of the study was the optimization of a chromatographic system for the analysis of cytisine and N-methylcytisine in various plant extracts as well as an investigation of the cytotoxic activities of selected alkaloids and plant extracts obtained from , and against various cancer cell lines.
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