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The role of videocapsule endoscopy in the diagnosis and follow-up of celiac disease: a scoping review.
Expert Rev Gastroenterol Hepatol
October 2024
Gastroenterology and Endoscopy Unit, IRCSS Humanitas Reserach Hospital, Rozzano, Milan, Italy.
Article Synopsis
- Videocapsule endoscopy (VCE) can aid in diagnosing celiac disease (CD) when initial tests are inconclusive and can also be useful in monitoring complex cases.
- A review of studies showed 186 patients underwent VCE for diagnosis, while 1,337 patients were followed up, highlighting its role in cases with negative serology or persistent symptoms.
- The findings indicated VCE is effective in identifying complications like refractory CD, but more research is needed for definitive conclusions about its overall utility in CD management.
[Gastrointestinal bleeding as debut of complicated celiac disease].
Rev Gastroenterol Peru
July 2024
Centro Endoscópico Pasteur. Montevideo, Uruguay.
Celiac disease (CD) is an autoimmune malabsorption syndrome that presents with intolerance to gluten (gliadin), a protein found in wheat. The most common symptoms are diarrhea, steatorrhea, weight loss, weakness, vitamin and mineral deficiency. The probability of developing complicated CD is relatively low, among its main manifestations we have refractory sprue, T-cell lymphoma and ulcerative jejunitis (UY) of which a few cases develop gastrointestinal bleeding.
View Article and Find Full Text PDFCT and MR Enterography in the Evaluation of Celiac Disease.
Radiographics
April 2024
From the Department of Radiology, Hospital Italiano de Buenos Aires, Teniente General Juan Domingo Perón 4190, Buenos Aires, Argentina C1199ABB (A.P., F.V., L.P.G., O.R., J.A.O.); and Mallinckrodt Institute of Radiology, Washington University St. Louis, St. Louis, Mo (R.T.).
Celiac disease is a common inflammatory disease of the small bowel that induces mucosal intestinal lesions. The disease is mediated by an immune response and triggered by the ingestion of gluten in genetically predisposed individuals. Gluten contains gliadin, a component found mostly in wheat, barley, and rye.
View Article and Find Full Text PDFAGA Clinical Practice Update on Management of Refractory Celiac Disease: Expert Review.
Gastroenterology
November 2022
Celiac Disease Program, Division of Gastroenterology, Hepatology, and Nutrition, Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, Ohio.
Description: The purpose of this expert review is to summarize the diagnosis and management of refractory celiac disease. It will review evaluation of patients with celiac disease who have persistent or recurrent symptoms, differential diagnosis, nutritional support, potential therapeutic options, and surveillance for complications of this condition.
Methods: This expert review was commissioned and approved by the American Gastroenterological Association (AGA) Institute Clinical Practice Updates Committee (CPUC) and the AGA Governing Board to provide timely guidance on a topic of high clinical importance to the AGA membership and underwent internal peer review by the CPUC and external peer review through standard procedures of Gastroenterology.
Clinical features of type 1 and 2 refractory celiac disease: Results from a large cohort over a decade.
Dig Liver Dis
February 2023
Department of Pathophysiology and Transplantation, University of Milan, Milan 20122, Italy; Center for Prevention and Diagnosis of Celiac Disease and Division of Gastroenterology and Endoscopy, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via F. Sforza 35, Milan 20122, Italy.
Objectives: Refractory celiac disease (RCeD) is a rare complication of celiac disease (CeD) with a severe prognosis. We describe a cohort of patients with RCeD, their clinical and histological features at diagnosis, after therapy and at lymphoma onset, and the rate and causes of death over a 17-year follow-up.
Methods: We retrospectively enrolled RCeD-I and RCeD-II patients attending our center between January 2002 and October 2019.
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