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This first-person essay explores wonder in the medical encounter from a patient's point of view, considering times when medical technology has given the author insight into her body and the wonder that has been evoked by these experiences. Two medical encounters are detailed: one in which post-polio vocal cord weakness was explored using a miniature camera, which evoked a sense of wonder at the process of evolution; and the second in which an MRI of the author's skull became a memento mori. The author reflects on the long processes of genetic mutation from single-celled organism to human being, and on the devolution after death to food for bacteria and insects.
View Article and Find Full Text PDFÉvaluation de la mise en œuvre des missions de service sanitaire en santé sexuelle en Île-de-France.
Glob Health Promot
November 2024
Université Paris Cité, Département de médecine générale, Paris, France - Paris (France).
Contexte: Le service sanitaire français, réalisé par des étudiants en santé (3 année), est un programme de promotion de la santé (PS) récent qui est encore peu évalué.
Objectif: Cette étude s'est intéressée au service mis en place dans la filière médecine à l'université Paris Cité, sur la thématique santé sexuelle. L'objectif de l'étude est d'évaluer des interventions réalisées par les étudiants en termes pédagogiques et en termes de bonnes pratiques en PS, sur les plans suivants : éthique, qualité du contenu et communication.
[Atypical alveolar echinococcosis with systemic involvement in a patient treated with dupilumab].
Rev Med Interne
June 2024
Service de médecine interne et d'immunologie clinique, Centre national de référence pour les maladies auto-immunes et systémiques (CNR RESO), Centre de compétences pour les déficits immunitaires primitifs, hôpitaux universitaires de Strasbourg, Strasbourg, France.
Introduction: Alveolar echinococcosis is an endemic parasitic disease prevalent in certain cold regions of the Northern Hemisphere, including Eastern France, Switzerland, Germany, Canada, and the United States. Widely underdiagnosed, it is associated with infection by Echinococcus multilocularis, a small tapeworm belonging to the cestode class, capable of causing multi-systemic involvement, particularly in elderly or immunocompromised patients.
Case Report: We present the case of an 82-year-old patient, immunocompromised due to prolonged corticosteroid therapy and treatment with dupilumab.
Nurses' work, work psychology, and the evolution & devolution of care provision in nursing homes: A scoping review.
Int J Nurs Stud Adv
December 2023
School of Nursing, McMaster University, Hamilton, Ontario, Canada.
Background: Societal aging is exerting profound impacts on providers of long-term care. Nurses provide much of the direct care in the long-term care sector, and they increasingly provide unit- and facility-level leadership and fill top administrative and clinical roles.The work health and quality of work life of long-term care nurses are emergent concerns and the foci of research across multiple disciplines.
View Article and Find Full Text PDFThe physical and evolutionary energy landscapes of devolved protein sequences corresponding to pseudogenes.
Proc Natl Acad Sci U S A
May 2024
Center for Theoretical Biophysics, Rice University, Houston, TX 77005.
Protein evolution is guided by structural, functional, and dynamical constraints ensuring organismal viability. Pseudogenes are genomic sequences identified in many eukaryotes that lack translational activity due to sequence degradation and thus over time have undergone "devolution." Previously pseudogenized genes sometimes regain their protein-coding function, suggesting they may still encode robust folding energy landscapes despite multiple mutations.
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