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CD3+ Tumor-Infiltrating Lymphocytes in Breast Carcinoma: Their Prognostic Role and Association With Clinical Parameters.
Cureus
December 2024
Pathology, BLDE (Deemed to be University) Shri B M Patil Medical College, Hospital and Research Centre, Vijayapura, IND.
Background Breast carcinoma cases are rising steadily and represent a major cause of mortality and morbidity in India. In response to breast carcinoma, the immune system is activated, resulting in lymphocyte infiltration in and around the tumor nests. This interaction between the tumor and immune system is the basis for studying tumor-infiltrating lymphocytes (TILs).
View Article and Find Full Text PDFValidity of Customized Branched Tissue Engineered Vascular Graft in a Porcine Model.
Ann Thorac Surg Short Rep
September 2023
Division of Cardiac Surgery, Department of Surgery, University of Chicago, Chicago, Illinois.
Background: Patient-specific, 3-dimensional printed, tissue engineered vascular grafts (3DTEVGs) are manufactured to optimize hemodynamic performance and to accommodate growth. We evaluate growth outcomes of 3DTEVGs compared with standard grafts for pulmonary artery reconstruction in porcine models.
Methods: Magnetic resonance imaging (MRI) with 4-dimensional flow data was acquired in porcine models (n = 8).
Maternal nutrition and offspring lung health: sex-specific pathway modulation in fibrosis, metabolism, and immunity.
Food Nutr Res
January 2025
Department of Gynaecology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Background: Maternal nutrition profoundly influences offspring health, impacting both prenatal and early postnatal development. Previous studies have demonstrated that maternal dietary habits can affect key developmental pathways in the offsprings, including those related to lung function and disease susceptibility. However, the sex-specific impact of a maternal high-salt diet (HSD) on offspring lung injury remains poorly understood.
View Article and Find Full Text PDFRare Primary Pericardial Mesothelioma on an [18F]FDG PET/CT Scan and Its Postchemotherapy Response Evaluation.
Indian J Nucl Med
November 2024
Department of Nuclear Medicine and PET CT, Bombay Hospital and Medical Research Centre, Mumbai, Maharashtra, India.
Primary pericardial mesothelioma is a highly aggressive and rare neoplasm that arises from the pericardial mesothelial cell and has a poor prognosis. The diagnosis is usually established by histological and immunohistochemical studies. Malignant mesothelioma most frequently occurs from the pleura (90%), less frequently from the peritoneum and pericardium (6%-10%), and very rarely from the tunica vaginalis in the testis.
View Article and Find Full Text PDFBenign Lung Adenoma Mimicking an Adenocarcinoma With Gene Fusion.
Ann Thorac Surg Short Rep
March 2023
Division of General Thoracic Surgery, Department of Surgery, University of California, Davis Health, Sacramento, California.
Bronchiolar adenoma is a benign neoplastic process thought to be derived from the bronchiolar epithelium. Particularly in small biopsy specimens, this entity can mimic lung cancer with important implications for management. We report the case of a 33-year-old man with a right upper lobe lung nodule, with initial biopsy identifying an adenocarcinoma with gene fusion.
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