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Accelerated Measurement of Carotid Plaque Volume Using Artificial Intelligence Enhanced 3D Ultrasound.
Ann Vasc Surg
January 2024
Division of Cardiovascular Sciences, University of Manchester, Manchester Academic Health Science, Manchester University NHS Foundation Trust, Manchester, UK; Manchester Vascular Centre, Manchester Academic Vascular Research and Innovation Centre (MAVRIC), Manchester University NHS Foundation Trust, Manchester, UK. Electronic address:
Background: Carotid plaque volume (CPV) can be measured by 3D ultrasound and may be a better predictor of stroke than stenosis, but analysis time limits clinical utility. This study tested the accuracy, reproducibility, and time saved of using an artificial intelligence (AI) derived semiautomatic software to measure CPV ("auto-CPV").
Methods: Three-dimensional (3D) ultrasound images for 121 individuals were analyzed by 2 blinded operators to measure auto-CPV.
Clinicopathological Correlation of Chronic Thromboembolic Pulmonary Hypertension: A Retrospective Study.
J Clin Med
November 2022
Department of Pathology, China-Japan Friendship Hospital, Beijing 100029, China.
The pathophysiology of chronic thromboembolic pulmonary hypertension (CTEPH) is largely unknown. Although pulmonary endarterectomy (PEA) is potentially curative, inoperable patients and persistent pulmonary hypertension (PH) following surgery remain a significant problem. In this study, we aim to describe the histopathological characteristics of CTEPH and explore the potential relationship between pulmonary arterial lesions, radiological parameters, and clinical manifestations.
View Article and Find Full Text PDFIncreased frequency of proangiogenic tunica intima endothelial kinase 2 (Tie2) expressing monocytes in individuals with type 2 diabetes mellitus.
Cardiovasc Diabetol
May 2022
Department of Pathology & Medical Biology - Pathology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, PO Box 30.001, Groningen, The Netherlands.
Background: Individuals with type 2 diabetes mellitus (T2DM) have an increased risk for developing macrovascular disease (MVD) manifested by atherosclerosis. Phenotypically and functionally different monocyte subsets (classical; CD14CD16, non-classical; CD14CD16, and intermediate; CD14CD16) including pro-angiogenic monocytes expressing Tie2 (TEMs) can be identified. Here we investigated monocyte heterogeneity and its association with T2DM and MVD.
View Article and Find Full Text PDFEffectiveness of an individualized home-based physical activity program in surgery-free non-endarterectomized asymptomatic stroke patients: a study protocol for the PACAPh interventional randomized trial.
Trials
February 2022
Atherosclerosis, Thrombosis and Physical Activity, LIBM EA7424, Université Lyon 1, University of Lyon, Lyon, France.
Background: Carotid atherosclerotic plaques remain silent until their rupture, which may lead to detrimental ischemic events such as strokes. This is due, in part, to intraplaque hemorrhages (IPH) and the resulting inflammatory processes, which may promote carotid plaque vulnerability. Currently, the benefits of carotid endarterectomy remain unclear for asymptomatic patients.
View Article and Find Full Text PDFAlternative femoral endarterectomies: technical aspects and short-term results.
Angiol Sosud Khir
September 2021
Centre for Vascular Surgery and Interventional Radiology, Tampere University Hospital, Tampere, Finland; Department of Surgery, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland; Finnish Cardiovascular Research Center, Tampere, Finland.
Background: Femoral endarterectomies are often performed by means of longitudinal arteriotomies with patching. Autologous and synthetic patches can be used. Synthetic patches in the groin may expose patients to infection.
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