We present a statistical framework for model calibration and uncertainty estimation for complex deterministic models. A Bayesian approach is used to combine data from observations, the deterministic model, and prior parameter distributions to obtain forecast distributions. A case study is presented in which the statistical framework is applied using the hydrogeochemical model (MAGIC) for an assessment of recovery from acidification of soils and surface waters at a long-term study site in Norway under different future acid deposition conditions. The water quality parameters are coupled with a simple dose-response model for trout population health. Uncertainties in model output parameters are estimated and forecast results are presented as probability distributions for future water chemistry and as probability distributions of future healthy trout populations. The forecast results are examined for three different scenarios of future acid deposition corresponding to three different emissions control strategies for Europe. Despite the explicit consideration of uncertainties propagated into the future forecasts, there are clear differences among the scenarios. The case study illustrates how inclusion of uncertainties in model predictions can strengthen the inferences drawn from model results in support of decision making and assessments.
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http://dx.doi.org/10.1021/es061091o | DOI Listing |
Ecol Lett
January 2025
School of Mathematical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia.
Ecosystem models are often used to predict the consequences of management interventions in applied ecology and conservation. These models are often high-dimensional and nonlinear, yet limited data are available to calibrate or validate them. Consequently, their utility as decision-support tools is unclear.
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December 2024
Department of Agricultural Entomology, Tamil Nadu Agricultural University, Coimbatore, 641003, India.
An efficient modified QuEChERS procedure was established for the simultaneous determination of 37 pesticide residues in fresh and processed edible button mushroom by employing GC/ GC-MS and LC-MS/MS. The effectiveness, reliability and accuracy of the method were assessed through validation parameters such as linearity, LOD, LOQ, precision, accuracy, uncertainty, and matrix effect. The linearity calibration for all the selected pesticides at standard concentrations (0.
View Article and Find Full Text PDFPDA J Pharm Sci Technol
December 2024
Nelson Labs, Romeinsestraat 12, 3001 Heverlee, Belgium.
Leachables in drug products and from medical devices can adversely affect patient health and thus must be identified and quantified. Accurate and protective quantitation in target analysis for leachables (and extractables as potential leachables) is accomplished via compound-specific calibration curves. Quantification in non-targeted analysis (NTA) is complicated by the variable relative response factors (RRFs) among and between individual leachables and the circumstance that the leachables are not known until the NTA is completed.
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December 2024
Department of Civil Engineering, Sardar Vallabhbhai National Institute of Technology Surat, Surat 395007, Gujarat, India. Electronic address:
This study provides crucial insights into sustainable water resource management in an agriculture-dominated, water-scarce region. The long-term hydrologic potential of the Purna sub-catchment (in India) was simulated using the Soil and Water Assessment Tool (SWAT) under a multimetric calibration approach. A comprehensive evaluation of the SWAT-simulated streamflows, incorporating graphical and quantitative assessments (i.
View Article and Find Full Text PDFWater Res
December 2024
GNS Science, New Zealand.
Source protection zone delineation has evolved over the past decades from fixed radius or analytical and numerical methods which do not consider uncertainty, to more complex stochastic numerical approaches. In this paper we explore options for delineating a source protection zone, while considering the inherent uncertainty involved in characterizing hydraulic conductivity. We consider a representative pumping well in an unconfined alluvial aquifer under steady-state flow conditions, with the hydraulic conductivity distribution inferred from borehole lithology data in the West Melton area near Christchurch, New Zealand.
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