Tricho-epitheliomas are benign tumors of the pilosebaccous apparatus. Multiple tricho-epithelioma form is particular. We report 2 new cases. 1) R.A., a 41 year-man with a 2 years history of histologically confirmed multiple tricho-epitheliomas. New lesions appeared during a 9 years-follow-up. Treatment was local excision of tumors. 2) M.B., a 41 year-man, have a 8 years history of 3 to 30 mm papulonodular lesions with telangiectasia, located on the face and associated to multiple milia, comedones and alopecia areata plaques. Histological study confirmed the diagnosis of multiple tricho-epitheliomas. Multiple tricho-epitheliomas is a genodermatosis it is often associated to other benign cutaneous tumors, mainly cylindromas and spiradenomas. It occurs in the 1st and 2nd decade. The lesions are symmetrically located on the face. Histological examination confirm the diagnosis. After repeated episodes, the lesions stabilize. Malignant changes are rare. Treatment is supported by aesthetic considerations. Various therapeutic means are available. Our reported cases are particular by the occurrence at relatively advanced age, the localization and the large size of some lesions. The associated alopecia areata in the 2nd patient could be fortuitous.
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Rev Med Brux
April 2007
Service de Dermatologie, C.H.U. H. Chker, Sfax, Tunisie.
Tricho-epitheliomas are benign tumors of the pilosebaccous apparatus. Multiple tricho-epithelioma form is particular. We report 2 new cases.
View Article and Find Full Text PDFBr J Dermatol
September 1991
Department of Dermatology, University Hospital Utrecht.
A melanin containing skin tumour of trichoepitheliomatic character, induced by a virus some 40 nm large, is described showing neither infiltrative nor metastasizing growth. The multiple, flat, mostly confluent tumour nodes appear in all parts of the skin, especially in dorsal skin, at the chin, eyes, and ears. The tumours are mostly blue black as a result of hemosiderin and melanin deposits; these pigmentations occur in connective-tissue cells, the tumour cells and the abounding keratinizing cysts.
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