After pure-tone audiometry, we have several sequences of threshold values. Usually, a multiple-line plot is used to present and compare data between measurements by overlaying them in a single graph. Calculation of air-bone gap and pure-tone average is widely accepted as an approach to simplify statistical handling of these data. The aim of this report was to introduce the Sofia profile plot using as examples different otosclerotic cases. This plot provides a simple way to visually present several pre- and postoperative hearing thresholds. Individual data points (pure-tone average and some other thresholds) are presented by marks in two-dimensional space. The vertical axis represents the time line and starts with the first threshold evaluation. The horizontal scale is used to mark hearing levels in decibels -- the right ear on the left of the vertical axis and the left ear on the right. The Sofia profile plot was developed especially for otosclerotic patients and permits the unambiguous marking of the onset of any individual unilateral or bilateral event (e.g. operation, revision, tinnitus) and thus to visually inspect its impact on hearing levels.
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http://dx.doi.org/10.1159/000098755 | DOI Listing |
Eur Heart J
January 2025
Department of Primary Care and Public Health, Imperial Centre for Cardiovascular Disease Prevention, School of Public Health, Imperial College London, White City Campus, 90 Wood Lane, London W12 0BZ, UK.
Background And Aims: Overweight and obesity are modifiable risk factors for atherosclerotic cardiovascular disease (ASCVD) in the general population, but their prevalence in individuals with heterozygous familial hypercholesterolaemia (HeFH) and whether they confer additional risk of ASCVD independent of LDL cholesterol (LDL-C) remains unclear.
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Nutr Metab Cardiovasc Dis
December 2024
Unit of Nutrition and Cancer, Cancer Epidemiology Research Programme, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.
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Eur J Cancer
January 2025
Department of Gynecology and Obstetrics, University of California, Irvine, CA, USA.
Aim: Cemiplimab has demonstrated significantly longer survival than physician's choice of chemotherapy in patients with recurrent cervical cancer after first-line platinum-containing chemotherapy. We report the final survival analysis from the phase III randomized study (EMPOWER-Cervical 1/GOG-3016/ENGOT-cx9).
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Eur J Pediatr
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Growth, Exercise, Nutrition and Development (GENUD) Research Group, Instituto Agroalimentario de Aragón (IA2), Faculty of Health Sciences, Universidad de Zaragoza, Instituto de Investigación Sanitaria de Aragón (IIS Aragón), 50009, Saragossa, Spain.
Unlabelled: Most of the available tools to assess adherence to Mediterranean diet (MedDiet) were constructed for adults, having limited applicability to children and adolescents. The aim of this study is to validate a specific questionnaire to assess adherence to MedDiet in children aged 3 to 6 years (MED4CHILD questionnaire). The validation was performed in a baseline examination of a cohort of children who were recruited in schools in seven cities.
View Article and Find Full Text PDFSensors (Basel)
December 2024
Institute of Optical Materials and Technologies, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Conventional Fourier domain Optical Coherence Tomography (FD-OCT) systems depend on resampling into a wavenumber () domain to extract the depth profile. This either necessitates additional hardware resources or amplifies the existing computational complexity. Moreover, the OCT images also suffer from speckle noise, due to systemic reliance on low-coherence interferometry.
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