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The ability of clostridium novyi-NT spores to induce apoptosis via the mitochondrial pathway in mice with HPV-positive cervical cancer tumors derived from the TC-1 cell line.
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Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
Background: A precise observation is that the cervix's solid tumors possess hypoxic regions where the oxygen concentration drops below 1.5%. Hypoxia negatively impacts the host's immune system and significantly diminishes the effectiveness of several treatments, including radiotherapy and chemotherapy.
View Article and Find Full Text PDFFunctional Characterization of , a Gene Coding an Aspartic Acid Protease in .
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Key Laboratory of Sustainable Crop Production in the Middle Reaches of the Yangtze River, College of Agriculture, Yangtze University, Jingzhou 434025, China.
Aspartic proteases (APs), hydrolases with aspartic acid residues as catalytic active sites, are closely associated with processes such as plant growth and development and fungal and bacterial pathogenesis. is the dominant pathogenic fungus that causes Fusarium head blight (FHB) in wheat. However, the relationship of APs to the growth, development, and pathogenesis of .
View Article and Find Full Text PDF[Construction of a recombinant strain expressing SpaA and CbpB of and evaluation of the strain immunogenicity in a mouse model].
Sheng Wu Gong Cheng Xue Bao
December 2024
College of Veterinary Medicine, Southwest University, Chongqing 402460, China.
To construct a recombinant strain expressing SpaA and CbpB of for oral administration, we constructed the recombinant plasmid pDG1730-CBJA by fusion PCR and seamless cloning. The plasmid was introduced into . KC strain by natural transformation, and the recombinant strain KC-- was screened out on the plate containing spectinomycin () and confirmed by PCR and starch degradation test.
View Article and Find Full Text PDFConsequences of "zombie-making" and generalist fungal pathogens on carpenter ant microbiota.
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Department of Biology, University of Central Florida, Orlando FL 32816, USA.
The bacterial microbiome of the ant has been well characterized across body regions and maturation levels. However, potential effects of entomopathogens on the gut microbiome, and the fungal communities therein, are yet to be assessed. Additionally, the mycobiome remains often overlooked despite playing a vital role in gut ecology with potential implications for health and infection outcomes.
View Article and Find Full Text PDFTaxonomic and genomic characterization of a siderophore-producing bacterium, Rhodoligotrophos ferricapiens sp. nov isolated from lettuce cultivation soil.
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Department of Systems Biotechnology, Chung-Ang University, Anseong, 17546, South Korea.
A Gram-stain-negative, aerobic, non-spore-forming, non-motile, coccus-shaped, and red-pigmented bacterial strain designated as CJ14 was isolated from lettuce cultivation soil in Yong-In, South Korea. Strain CJ14 grew optimally on Luria-Bertani agar at 37 ℃ and pH 7.0 in the absence of NaCl.
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