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Similar Publications

Shoshin Beriberi in a Child With Intestinal Failure: A Case Report.

Crit Care Explor

December 2024

Section of Pediatric Critical Care, Department of Pediatrics, Cumming School of Medicine, University of Calgary, Alberta Children's Hospital, Calgary, AB, Canada.

Background: Acute illness states with increased metabolic demand can precipitate severe thiamine deficiency if physiologic needs exceed endogenous stores and supplementation. Patients with preexisting risk factors such as parenteral nutrition (PN) dependence, eating disorders, gastrointestinal disorders, or surgeries are especially vulnerable.

Case Summary: A 9-year-old girl with short bowel syndrome receiving long-term PN, including standard thiamine supplementation, presented with refractory shock following aspiration.

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Article Synopsis
  • * This study compared infants diagnosed with TRPHTN and acute respiratory infection (ARI) to understand the differences in their presentation and investigated genetic variations in Thiamine transporter genes without finding conclusive results.
  • * The research involved 82 infants, revealing that TRPHTN had specific symptoms and risk factors, while lactate and pulmonary pressure measurements proved effective in identifying thiamine deficiency issues.
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Shoshin beriberi is a fulminant form of wet beriberi, but there are no large-scale studies detailing the clinical features of this disease. We investigated the clinical features and outcomes of Shoshin beriberi using data from a nationwide database in Japan.Using the Diagnosis Procedure Combination database, we identified patients with Shoshin beriberi between July 2010 and March 2021.

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Thiamine deficiency presents as dry and wet beriberi. Wet beriberi is a complication of the cardiovascular system. Acute form of wet beriberi known as Shoshin beriberi is an acute presentation of cardiogenic shock which is rapidly reversed with thiamine administration.

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