A retrospective study of 8772 children's records at the department of ophthalmology, North Bengal Medical College, Sushrutanagar, Darjeeling, West Bengal, India was conducted to collect the data on visual loss relating age, gender, degree and aetiology with an object of delineation of the profile of visual loss in children of particular area encircling that referral centre. Out of 8772 children, 126 children were detected to be suffering from visual loss. Of these 126 children, 88(69.84%) were males, 38(30.16%) were females, 75 children (59.52%) had low vision, 51(40.48%) had blindness. The causes of visual loss were cataract in 42 cases (33.33%), corneal pathology in 30(23.80%), high refractive error in 15(11.90%), glaucoma in 14(11.11%), retinal disease in 12(9.52%), global anomalies in 10 (7.94%) and lesion in the higher visual pathway in 3 cases (2.38%). Information obtained from the study possesses a definite role in understanding the background of visual loss in children of a particular area and planning the strategy to control childhood blindness by identification of preventable and treatable causes of blindness.
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West Afr J Med
September 2024
Department of Ophthalmology, University of Calabar, Calabar, Cross River State, Nigeria.
Background: Strabismus is a potential cause of ocular morbidity.
Objective: The aim of this study was to determine the frequency, types of manifest strabismus and co-morbidities among patients attending a referral paediatric ophthalmology and strabismus clinic in Calabar, Nigeria.
Methods: A retrospective review of case-notes of patients attending the paediatric ophthalmology and strabismus clinic from January 1, 2017 to December 31, 2019 was done.
Eur J Orthop Surg Traumatol
January 2025
Duzce University, Düzce, Turkey.
Purpose: Blood loss and pain management are significant concerns in total knee arthroplasty (TKA). Tranexamic acid (TA) and cryotherapy have been used separately to address these issues, but their comparative effectiveness is not well studied. This study aimed to evaluate the efficacy of intravenous TA and cryotherapy in reducing blood loss and improving clinical outcomes after TKA.
View Article and Find Full Text PDFFront Biosci (Landmark Ed)
January 2025
Department of Neurology, Jinshan Hospital, Fudan University, 201508 Shanghai, China.
Background: Neuronal cholesterol deficiency may contribute to the synaptopathy observed in Alzheimer's disease (AD). However, the underlying mechanisms remain poorly understood. Intact synaptic vesicle (SV) mobility is crucial for normal synaptic function, whereas disrupted SV mobility can trigger the synaptopathy associated with AD.
View Article and Find Full Text PDFEur Stroke J
January 2025
Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Background: We aimed to assess impairments on health-related quality of life, and mental health resulting from Retinal artery occlusion (RAO) with monocular visual field loss and posterior circulation ischemic stroke (PCIS) with full or partial hemianopia using patient-reported outcome measures (PROMs).
Methods: In a prospective study, consecutive patients with acute RAO on fundoscopy and PCIS on imaging were recruited during their surveillance on a stroke unit over a period of 15 months. Baseline characteristics were determined from medical records and interviews.
J Integr Neurosci
January 2025
Neuroscience Department, University of Connecticut Health, School of Medicine, Institute for Systems Genomics, Farmington, CT 06030, USA.
Background: In neuroscience, Ca imaging is a prevalent technique used to infer neuronal electrical activity, often relying on optical signals recorded at low sampling rates (3 to 30 Hz) across multiple neurons simultaneously. This study investigated whether increasing the sampling rate preserves critical information that may be missed at slower acquisition speeds.
Methods: Primary neuronal cultures were prepared from the cortex of newborn pups.
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