Background: Very few references on the usability of presence of asbestos bodies (AB) in induced sputum as an indicator of asbestos exposure are to be found in the scientific literature.

Objectives: The purpose of this study was to prove whether the presence of AB in induced sputum is a valid assessor of asbestos exposure.

Method: This was achieved by comparing the above-mentioned method with the search for AB in bronchoalveolar lavage (BAL) fluid and repeating the trials over time in order to study the reproducibility of the results.

Results: There was good agreement of results for the presence/absence of AB in induced sputum and in BAL among subjects who were environmentally exposed and those with 'a medium-high risk occupational exposure (100%), and poor agreement (66%) among subjects with a low risk occupational exposure. Agreement of results regarding the amount of particles per test was low. The method showed a sufficient reproducibility level (Cohen K=0.5).

Conclusion: Although the presence of asbestos bodies in induced sputum cannot replace bronchoalveolar lavage, it can however be used as a screening test for selecting subjects who should undergo BAL.

Download full-text PDF

Source

Publication Analysis

Top Keywords

induced sputum
20
presence asbestos
12
asbestos bodies
12
bodies induced
12
sputum indicator
8
indicator asbestos
8
bronchoalveolar lavage
8
risk occupational
8
occupational exposure
8
asbestos
6

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!