The author suggests a graphic method for plasminogen estimation. The euglobulin fraction lysis is recorded in the hemocoagulographer cuvette, this essentially improving the accuracy of studies.
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Posttraining Network Compression for 3D Medical Image Segmentation: Reducing Computational Efforts via Tucker Decomposition.
Radiol Artif Intell
January 2025
From the Department of Radiology, University Hospital, LMU Munich, Marchioninistr 15,81377 Munich, Germany (T.W., J.D., M.I.); Department of Statistics, LMU Munich, Munich, Germany (T.W., D.R.); and Munich Center for Machine Learning, Munich, Germany (T.W., J.D., D.R., M.I.).
Purpose To investigate whether the computational effort of 3D CT-based multiorgan segmentation with TotalSegmentator can be reduced via Tucker decomposition-based network compression. Materials and Methods In this retrospective study, Tucker decomposition was applied to the convolutional kernels of the TotalSegmentator model, an nnU-Net model trained on a comprehensive CT dataset for automatic segmentation of 117 anatomic structures. The proposed approach reduced the floating-point operations (FLOPs) and memory required during inference, offering an adjustable trade-off between computational efficiency and segmentation quality.
View Article and Find Full Text PDFIdentifying Disease Associated Multi-Omics Network With Mixed Graphical Models Based on Markov Random Field Model.
Genet Epidemiol
January 2025
Interdisciplinary Program of Bioinformatics, College of Natural Science, Seoul National University, Seoul, South Korea.
In this article, we proposed a new method named fused mixed graphical model (FMGM), which can infer network structures associated with dichotomous phenotypes. FMGM is based on a pairwise Markov random field model, and statistical analyses including the proposed method were conducted to find biological markers and underlying network structures of the atopic dermatitis (AD) from multiomics data of 6-month-old infants. The performance of FMGM was evaluated with simulations by using synthetic datasets of power-law networks, showing that FMGM had superior performance for identifying the differences of the networks compared to the separate inference with the previous method, causalMGM (F1-scores 0.
View Article and Find Full Text PDFCustomizable large-scale HPLC fraction collection using low-cost 3D printing.
HardwareX
March 2025
Molecular and Systems Pharmacology Program, Emory University, Atlanta, GA, USA.
High-performance liquid chromatography (HPLC) is an invaluable technique that has been used for many decades for the separation of various molecules. The reproducible collection of eluates from these systems has been significantly improved via its automation by fraction collection systems. Current commercially available fraction collectors are not easily customizable, incompatible with other platforms, and come with a large cost barrier making them inaccessible to many researchers.
View Article and Find Full Text PDFZ-residual diagnostic tool for assessing covariate functional form in shared frailty models.
J Appl Stat
May 2024
Department of Community Health and Epidemiology, Faculty of Medicine, Dalhousie University, Halifax, CA, Canada.
Survival analysis often involves modeling hazard functions while considering frailty to account for unobserved cluster-level factors in clustered survival data. Shared frailty models have gained popularity for this purpose, but assessing covariate functional form in these models presents unique challenges. Martingale and deviance residuals are commonly used for visually assessing covariate functional form against continuous covariates.
View Article and Find Full Text PDFA one health approach for integrated vector management monitoring and evaluation.
One Health
June 2025
Univ. Rennes, EHESP, Inserm, IRSET UMR_S 1085, F-3500 Rennes, France.
The French Agency for Food, Environmental and Occupational Health & Safety (Anses) has set up a multidisciplinary working group (WG) to develop an innovative One Health approach for the monitoring and evaluation of an integrated vector management system (IVMS) on a territorial scale. Four existing evaluation guidelines and methods have been combined into a semi-quantitative evaluation approach that takes into account all the dimensions of an integrated process. We propose a set of 34 criteria divided into three sections (objectives and management, implementation, integration) that correspond to the main functional components of an IVMS.
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