An architectural framework for an adverse drug event surveillance system.

Much effort has focused on detecting as many adverse drug events (ADEs) as possible, as soon possible. An ADE surveillance system (ADESS) is a computerized surveillance system that detects ADEs automatically, by analyzing medication orders, laboratory results, and medical records. We propose a new ADESS architectural framework using the object-oriented component-based development (OOCBD) methodology to extract and analyze ADEs automatically, with a minimal server-side workload.