Hyperbaric oxygen for adjuvant therapy for chronically recurrent mandibular osteomyelitis in childhood and adolescence.

J Oral Maxillofac Surg

Hyperbaric Oxygen Unit, Institute of Diagnostic Radiology, Institute of Diagnostic Radiology and the Clinic of Maxillofacial Plastic Surgery, Westdeutsche Kieferklinik, University Hospital Düsseldorf, Düsseldorf, Germany.

Published: February 2007

Purpose: In this article, the question of whether adjuvant hyperbaric oxygen therapy (HBO) has a positive effect when treating chronically recurrent mandibular osteomyelitis in children and adolescents is discussed.

Patients And Methods: Over a period of 5 years, 4 cases were observed, 3 of which were submitted to adjuvant HBO. Details on the modalities of this type of treatment and the simultaneous intravenous administration of high doses of antibiotics are reported.

Results: All 3 patients have been free of any symptoms from 20 to 74 months (mean, 41 months) and therefore may most likely be regarded as healed.

Conclusion: The small number of cases does not allow a final statement on the extent to which HBO contributed to the positive outcome. However, in our opinion, HBO is a most promising therapeutic option. Finally, the problems involved in prospective randomized studies of this rare disease are discussed in detail.

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http://dx.doi.org/10.1016/j.joms.2005.11.106DOI Listing

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