Recently, a novel heart syndrome, mimicking acute coronary syndrome, was described. Patients commonly present with chest pain, ST segment elevation, prolonged QT interval and slight elevation of cardiac enzymes and biomarker levels, despite the absence of significant coronary artery disease. Because of the peculiar left ventricular apical ballooning shape, given by characteristic regional wall motion abnormalities consisting in apical akinesis and basal hyperkinesis, this syndrome was named "Takotsubo" cardiomyopathy, after a round Japanese octopus fishing pot. An episode of emotional or physical stress, including a number of noncardiac illnesses, can be often identified as a trigger. Its unique features include also a strong female predominance and a complete rapid resolution. The management of this syndrome consists mainly in supportive and symptomatic therapy. The evolution, although mainly uneventful, can be complicated, rarely, by left ventricular rupture, making thus the takotsubo cardiomyopathy a newly recognized cause of sudden death. We present some data on the epidemiology, pathogenesis, clinical picture and management of this peculiar form of heart disease, which, although easily confounded with an acute coronary syndrome, has emerged as a unique nosologic entity.
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Int J Cardiovasc Imaging
December 2024
Cardiothoracic Imaging, Department of Radiology, University of Washington, Seattle, USA.
Stress/Takotsubo cardiomyopathy (TCM) is a transient regional left ventricular (LV) systolic dysfunction, often mimicking acute myocardial infarction with normal coronary arteries. Rarely TCM can mimic hypertrophic cardiomyopathy (HCM). We describe a case where TCM presented with LV hypertrophy (LVH) and left ventricular outflow tract obstruction (LVOTO) which resolved on follow-up.
View Article and Find Full Text PDFClin Pract Cases Emerg Med
November 2024
Albert Einstein Medical Center, Department of Emergency Medicine, Philadelphia, Pennsylvania.
Case Presentation: We present a case of a 50-year-old patient who presented to the emergency department with palpitations, nausea, vomiting, and chest discomfort. She was found to have a reduced ejection fraction and basal wall hypokinesis on point-of-care ultrasound concerning for reverse takotsubo cardiomyopathy.
Discussion: Reverse takotsubo cardiomyopathy is a rare variant of takotsubo cardiomyopathy and involves basal ballooning instead of apical ballooning.
Pak J Med Sci
December 2024
Professor Asif Bashir, Punjab Institute of Neurosciences, Lahore, Punjab, Pakistan.
Background & Objective: Takotsubo cardiomyopathy (TCM), manifests as left ventricular dysfunction triggered by physical or emotional stress. It leads to higher morbidity in epileptic patients and can progress to complications. To find out the correlation between Takotsubo cardiomyopathy and epilepsy and to investigate pathophysiology and associated types of epilepsy.
View Article and Find Full Text PDFInt J Emerg Med
December 2024
Department of Emergency Medicine, Lithuanian University of Health Sciences, A. Mickevičiaus g. 9, Kaunas, LT-44307, Lithuania.
Background: Carbon monoxide (CO) poisoning is a serious yet frequently overlooked condition with diverse and nonspecific clinical presentations. The analysis of Lithuanian statistics reveals fluctuations in patient admissions and consultations through the poisoning center over a four-year period, with notable variations in fatality rates. Despite these trends, CO poisoning remains a significant public health concern due to its potential for severe long-term sequelae or death.
View Article and Find Full Text PDFIsr Med Assoc J
December 2024
Department of Internal Medicine, Galilee Medical Center, Nahariya, Israel, Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
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