Based on optoacoustic effect, time-resolved optoacoustic technique effectively combines optical technology with acoustic technology and partly overcomes the biological tissue's scatter characteristics which might influence the results of measurement. Optoacoustic technique has the advantages of high sensitivity and high resolution and has been widely applied in biomedicine field. In this paper, the measuring principles, the key technique, application and future direction of this technique are synthetically reviewed to promote the research in theory and application in the future.
Download full-text PDF |
Source |
---|
Photoacoustics
February 2025
Optics and Photonics Group, Faculty of Engineering, University of Nottingham, University Park, Nottingham, NG7 2RD, Nottinghamshire, United Kingdom.
In this paper, we demonstrate for the first time the focusing of gigahertz coherent phonon pulses propagating in water using picosecond ultrasonics and Brillouin light scattering. We achieve this by using planar Fresnel zone plate and concave lenses with different focal lengths. Pump light illuminating the optoacoustic lens generates a focusing acoustic field, and Brillouin scattered probe light allows the acoustic field to be continuously monitored over time.
View Article and Find Full Text PDFInt J Mol Sci
February 2024
Institut für Anorganische und Analytische Chemie, Universität Münster, Corrensstraße 28/30, 48149 Münster, Germany.
Metal phthalocyaninates and their higher homologues are recognized as deep-red luminophores emitting from their lowest excited singlet state. Herein, we report on the design, synthesis, and in-depth characterization of a new class of dual-emissive (visible and NIR) metal naphthalocyaninates. A 4-,-dimethylaminophen-4-yl-substituted naphthalocyaninato zinc(II) complex () and the derived water-soluble coordination compound () exhibit a near-infrared fluorescence from the lowest ligand-centered state, along with a unique push-pull-supported luminescence in the visible region of the electromagnetic spectrum.
View Article and Find Full Text PDFImages rendered with common optoacoustic system implementations are often afflicted with distortions and poor visibility of structures, hindering reliable image interpretation and quantification of bio-chrome distribution. Among the practical limitations contributing to artifactual reconstructions are insufficient tomographic detection coverage and suboptimal illumination geometry, as well as inability to accurately account for acoustic reflections and speed of sound heterogeneities in the imaged tissues. Here we developed a convolutional neural network (CNN) approach for enhancement of optoacoustic image quality which combines training on both time-resolved signals and tomographic reconstructions.
View Article and Find Full Text PDFInvest Ophthalmol Vis Sci
March 2021
Medical Laser Center Lübeck, Lübeck, Germany.
Purpose: New lasers with a continuous wave power exceeding 15 W are currently investigated for retinal therapies, promising highly localized effects at and close to the Retinal Pigment Epithelium (RPE). The goal of this work is to evaluate mechanisms and thresholds for RPE cell damage by means of pulse durations up to 50 µs.
Methods: A diode laser with a wavelength of 514 nm, a power of 15 W, and adjustable pulse durations between 2 µs and 50 µs was used.
The recently developed optoacoustic tomography systems have attained volumetric frame rates exceeding 100 Hz, thus opening up new venues for studying previously invisible biological dynamics. Further gains in temporal resolution can potentially be achieved via partial data acquisition, though a priori knowledge on the acquired data is essential for rendering accurate reconstructions using compressed sensing approaches. In this work, we suggest a machine learning method based on principal component analysis for high-frame-rate volumetric cardiac imaging using only a few tomographic optoacoustic projections.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!