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Using Artificial Intelligence to Support Informed Decision-Making on Mutation Testing.
JCO Precis Oncol
October 2024
Digital Science, London, United Kingdom.
Purpose: Precision oncology relies on accurate and interpretable reporting of testing and mutation rates. Focusing on the mutations in advanced colorectal carcinoma, non-small-cell lung carcinoma, and cutaneous melanoma, we developed a platform displaying testing and mutation rates reported in the literature, which we annotated using an artificial intelligence (AI) and natural language processing (NLP) pipeline.
Methods: Using AI, we identified publications that likely reported a testing or mutation rate, filtered publications for cancer type, and identified sentences that likely reported rates.
Botryomycosis Secondary to Masquerading as Mycetoma in a 46-year-old Filipino Female.
Acta Med Philipp
September 2024
Department of Dermatology, Philippine General Hospital, University of the Philippines Manila.
Article Synopsis
- * Imaging and biopsy techniques revealed granulomatous dermatitis without fungal involvement, leading to identification of a specific bacterial pathogen, which was effectively treated with co-trimoxazole for a year.
- * This case marks the first documented instance of botryomycosis in the Philippines and emphasizes the need for awareness of this condition among healthcare professionals dealing with chronic skin infections.
The Immune Memory Response of In Vitro-Polarised Th1, Th2, and Th17 Cells in the Face of Ovalbumin-Transgenic in a Mouse Model.
Int J Mol Sci
August 2024
Centre for Animal Biotechnology, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.
Th1 and Th2 cytokines determine the outcome of infection and immune protection depends mainly on memory T cells induced during vaccination. This largely hinges on the nature and type of memory T cells produced. In this study, transgenic strains expressing membrane-associated ovalbumin (mOVA) and soluble ovalbumin (sOVA) were used as a model to study whether fully differentiated Th1/Th2 and Th17 cells can recall immune memory and tolerate pathogen manipulation.
View Article and Find Full Text PDFProven Cutaneous Mucormycosis in a COVID-19 Patient: A Case Report and Literature Review.
Iran J Pathol
February 2024
Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
There has been a rise in COVID-19-associated mucormycosis (CAM) cases, particularly in low-income countries. We describe a case of primary cutaneous mucormycosis after recovering from COVID-19 in a kidney transplant recipient who had a known case of diabetes mellitus. The patient developed cutaneous ulcers due to Rhizopus oryzae in the right hand.
View Article and Find Full Text PDFRelapse or recall? Docetaxel-associated re-emergence of paraneoplastic dermatomyositis.
JAAD Case Rep
August 2024
Department of Dermatology, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
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