The experience of sampling of fish tissues for chlororganic pesticides (COP) content or its metabolites is generalized. The greatest quantity of these substances concentrate in brain and liver tissues and in brain tissues the pesticides accumulate during all the period of ontogenesis, but in liver - only during last months of active feeding period. According to the difference in pesticide content in fish tissues in spring and autumn we can localize the source of COP contamination of water fauna and terrestrial ecosystems of different protected areas possessing water bodies. It has been demonstrated on example of white fishes sensitive to COP and inhabiting the northern regions of Hallarctic as well as on sazan - a representative of ichthyofauna of the river Vakhsh in a deserted reserve the "Tiger's Walley".
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