Introduction: Clival chordomas are rare tumors, especially in the pediatric population. In this report, we present the case of a 3-year-old boy who was found to have a large posterior pharyngeal, clival, and posterior fossa tumor detected on a CT scan after a closed head injury.
Discussion: Further questioning revealed a history of ataxia and dysphagia. Imaging confirmed severe extrinsic brain stem compression. The tumor was resected in multiple stages utilizing a minimally invasive endoscopic endonasal technique along with open transfacetal, transcondylar approach through the carotid-vertebral window. The child suffered no permanent complications as a result of our treatment and his dysphagia significantly improved. Although a complete resection was not feasible due to vascular encasement by the tumor, extensive decompression was obtained with minimal morbidity.
Conclusion: We present this case to illustrate a new paradigm of skull base surgical approaches for large clival lesions in pediatric patients that allows aggressive resection with minimal morbidity.
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http://dx.doi.org/10.1007/s00381-006-0281-6 | DOI Listing |
Neuroophthalmology
November 2024
Department of Ophthalmology, Bangalore Medical College and Research Institute, Bangalore, India.
Transorbital Neuro Endoscopic Surgery (TONES) stands at the forefront of neurosurgical innovation, providing a transformative approach for accessing intricate intracranial vascular lesions within the orbit. The versatility of TONES extends beyond orbital confines, reaching into challenging territories such as the anterior cranial fossa, making it a promising option for lesions extending into the orbital region. This review explores the historical evolution, technical intricacies, and clinical applications of TONES, emphasizing its role in managing vascular lesions.
View Article and Find Full Text PDFEpilepsy Behav Rep
March 2025
Servicio de Neurología, Fundación Valle del Lili, Cali, Colombia.
Encephaloceles are abnormal protrusions of brain tissue, meninges, and cerebrospinal fluid that result from defects in the skull base or cranial vault. These abnormalities can lead to seizure disorders and focal pharmacoresistant epilepsies. However, clinical suspicion and diagnosis are frequently delayed due to the significant challenges in interpreting initial imaging.
View Article and Find Full Text PDFJ Neurosci Methods
February 2025
Institute for Cognitive Neuroscience, Neuronal Basis of Learning, Department of Psychology, Ruhr University Bochum, Bochum, Germany. Electronic address:
Background: Chronic implants for neural data acquisition must meet several criteria that can be difficult to integrate. Surgical procedures should be as short as possible to reduce unnecessary stress and risks, yet implants must precisely fit to the location of interest and last long periods of time. Implants also must be lightweight but stable enough to withstand the subject's daily life and experimental needs.
View Article and Find Full Text PDFGeroscience
February 2025
Department of Neurology, University Medicine Greifswald, Greifswald, Germany.
Embodied processing is crucial for visual perspective taking (VPT), with evidence from non-invasive transcranial direct current stimulation (tDCS) suggesting a causal role of the right temporoparietal junction (rTPJ). However, it is not known whether such embodied factors are maintained in older adults or whether rTPJ-tDCS has comparable effects in advanced age. We employed a balanced and sham-tDCS controlled, double-blinded, cross-over design, including two randomized experimental groups of healthy older adults, receiving focal tDCS over either the rTPJ (n = 30), or a control region in the dorsomedial prefrontal cortex (dmPFC, n = 30).
View Article and Find Full Text PDFOper Neurosurg (Hagerstown)
February 2025
Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.
Background And Objectives: Managing dolichoectatic vertebrobasilar artery aneurysms requires a multifaceted approach. Revascularization of the posterior circulation with a high-flow bypass is part of the flow reversal paradigm. Performing a robust high-flow bypass and addressing the aneurysm through the same approach smooths the operative intervention.
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