Objective: The aging of the neck is a combination of accumulated submental fat, platysmal banding, and redundant skin. Traditional face- and neck-lifting procedures successfully address these components. Unfortunately, the cost, both in terms of downtime and expense, often becomes prohibitive for a large section of the interested patient population. For select male patients, direct excision of the turkey jowl deformity with a straight-line closure offers a novel alternative.
Design: A review of 100 consecutive cases of direct excision of turkey jowl deformity procedures was performed. Minimal follow-up was 1 year. All surgical procedures were performed in the office setting with local anesthesia.
Results: Eight patients had extrusions of suture without recurrence of banding. Four patients required steroid injections for mild scar hypertrophy; 2 of these patients requested minor scar revisions 1 year later. There were no cases of postoperative bleeding, infection, or nerve injury. All 100 patients were satisfied with the overall cosmesis, and none had revision jowl surgery.
Conclusions: Direct excision of the turkey jowl with a straight-line closure offers a major improvement in the aging neck with minimal downtime, expense, and complication rate. This procedure can be easily accomplished and safely performed in an office environment.
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http://dx.doi.org/10.1001/archfaci.9.1.56 | DOI Listing |
Aesthetic Plast Surg
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Department of Plastic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.
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Siberian Branch of the Russian Academy of Sciences Institute of Chemical Biology and Fundamental Medicine, 8 Lavrentieva Ave., 630090 Novosibirsk, Russia.
The apurinic/apyrimidinic site (AP site) is a highly mutagenic and cytotoxic DNA lesion. Normally, AP sites are removed from DNA by base excision repair (BER). Methoxyamine (MOX), a BER inhibitor currently under clinical trials as a tumor sensitizer, forms adducts with AP sites (AP-MOX) resistant to the key BER enzyme, AP endonuclease.
View Article and Find Full Text PDFG3 (Bethesda)
January 2025
W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
The mosquito Aedes aegypti is an emerging model insect for invertebrate neurobiology. We detail the application of a dual transgenesis marker system that reports the nature of transgene integration with circular donor template for CRISPR-Cas9-mediated homology-directed repair at target mosquito chemoreceptor genes. Employing this approach, we demonstrate the establishment of cell-type-specific T2A-QF2 driver lines for the A.
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Hospital of Stomatology, Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.
Oral diseases such as dental caries, periodontitis, and oral cancer are prevalent and present significant challenges to global public health. Although these diseases are typically treated through procedures like dental preparation and resin filling, scaling and root planning, or surgical excision, these interventions are often not entirely effective, and postoperative drug therapy is usually required. Traditional drug treatments, however, are limited by factors such as poor drug penetration, significant side effects, and the development of drug resistance.
View Article and Find Full Text PDFJPRAS Open
March 2025
Sir Charles Gairdner Hospital, Nedlands, Perth, Western Australia, 6009.
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