A rare disease.

Crit Care

Department of Intensive Care Medicine, Onze Lieve Vrouwe Gasthuis, HM Amsterdam, The Netherlands.

Published: June 2007

Thrombocytopenia is a common finding in critically ill patients. Heparin-induced thrombocytopenia is an infrequent cause of a low platelet count. Intensivists should use the diagnostic classification system developed by the International Society on Thrombosis and Haemostasis to diagnose heparin-induced thrombocytopenia. The clinical relevance of the presence of anti-heparin/platelet factor 4 complex autoantibodies in the absence of clinical heparin-induced thrombocytopenia remains unknown.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151898PMC
http://dx.doi.org/10.1186/cc5131DOI Listing

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