Diastereocontrolled synthesis of enantioenriched 3,4-disubstituted beta-prolines.

J Org Chem

Laboratoire de Chimie Organique, UMR 7611, FR2769, Université Pierre et Marie Curie, Tour 44-45, 2ème étage, Case 183, 4 place Jussieu, 75252 Paris Cedex 05, France.

Published: January 2007

Enantioenriched 3,4-disubstituted beta-prolines have been prepared with a high diastereocontrol through a carbometalation reaction or through a domino Michael addition/carbometalation reaction.

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Source
http://dx.doi.org/10.1021/jo061603hDOI Listing

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