Objective: Patients who underwent heart transplantation (HTX) experience a reduction in the elevation that is usual in systolic blood pressure during exercise testing. Of unknown origin, this phenomenon varies in frequency and intensity. The aim of this study was to analyze the relationship between systolic blood pressure increase (delta SBP) and clinical aspects, as well as variables measured during exercise testing (ET) and dobutamine stress echocardiography (DSE) in patients in the late post-transplantation course.
Methods: Forty-five men, mean age 49.04 +/- 10.19, underwent clinical assessment, ET and DSE 40.91 +/- 27.46 months after heart transplantation. Left ventricular wall motion score index and ejection fraction were assessed. Delta SBP < 35 mmHg during ET was considered abnormal (SBC,1995).
Results: No significant correlation was found between delta SBP and post-transplantation time, graft ischemic time, history of rejection, diltiazem dosage, oxygen uptake, ejection fraction, and wall motion score index (WMSI). Delta SBP was normal in 17 patients (Group I) and abnormal in 28 (Group II). Patients of both groups did not differ significantly in regard to clinical features and ET and DSE results.
Conclusion: Unlike other populations, no correlation was found between delta SBP during exercise testing and clinical condition or left ventricular function in heart transplant patients. Pathophysiological factors associated with delta SBP reduction during exercise testing remain unknown.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1590/s0066-782x2006001800013 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Central vs. Brachial Blood Pressure and Pulse Pressure Amplification for Mortality Risk Prediction in Patients Undergoing Coronary Angiography.
Am J Hypertens
December 2024
Fifth Department of Medicine, University Medical Center Mannheim UMM, Faculty of Medicine of the University of Heidelberg, Mannheim, Germany.
Background: Arterial hypertension is a significant risk factor for cardiovascular (CV) morbidity and mortality. Although central blood pressure (BP) evaluation is considered the gold standard, the reliability of non-invasive measurements remains unclear. Therefore, we compared the predictive value of invasively measured central BP with non-invasively measured brachial BP and analyzed pulse pressure (PP) amplification (delta-PP; difference between central and peripheral PP) as an independent predictor of mortality.
View Article and Find Full Text PDFPower exercises with elastic bands combined with endurance training improve pulse pressure, systolic blood pressure, and functional parameters in older adults.
Blood Press Monit
November 2024
Postgraduate Program in Physical Education, Federal University of Maranhão.
Objective: This study aimed to investigate the effects of power training (PT) using elastic bands combined with endurance training (ET) on pulse pressure (PP), systolic (SBP) and diastolic blood pressures (DBP), autonomic response (AR), and functional parameters in older adults.
Methods: Thirty participants were randomly assigned to the control group (n = 15) and the intervention group (IG) (n = 15). IG participants performed PT with elastic bands combined with ET twice weekly for 8 weeks.
Impact of Pre-Hospital Intravenous Infusion on Physiological Parameters in Severe Trauma Patients.
Cureus
October 2024
Graduate School of Emergency Medical System, Kokushikan University, Tokyo, JPN.
Introduction The relationship between pre-hospital intravenous (IV) infusions administered by emergency life-saving technicians (ELSTs) to trauma patients in shock and the resulting variability in their vital signs before hospital arrival remains unclear. In 2014, Japan approved the use of lactated Ringer's solution via IV by ELSTs for patients aged 15 and older with non-cardiac arrest and shock symptoms not caused by cardiogenic factors. However, the impact of pre-hospital IV infusions on physiological parameters in severely injured trauma patients is still unknown.
View Article and Find Full Text PDFAntihypertensive effects and changes in extracellular water content by mineralocorticoid receptor antagonists in patients with primary aldosteronism.
Hypertens Res
November 2024
Department of Endocrinology, Metabolism, Rheumatology and Nephrology, Faculty of Medicine, Oita University, Yufu, Japan.
In primary aldosteronism (PA), non-suppressible excessive aldosterone secretion due to dietary salt intake significantly contributes to hypertension and cardiovascular complications. Blocking the overactivation of mineralocorticoid receptors (MRs) with mineralocorticoid receptor antagonists (MRAs) is a cornerstone for the medical treatment of PA. However, the role of MRAs in controlling hypertension remains unclear.
View Article and Find Full Text PDFThe association between intra-arrest arterial blood pressure and return of spontaneous circulation in out-of-hospital cardiac arrest.
Resuscitation
December 2024
Department of Research, Audit, Innovation, and Development (RAID), East Anglian Air Ambulance, Norwich, UK; Blizard Institute, Queen Mary University of London, London, UK; Academic Department of Military Medicine, Royal Centre for Defence Medicine (Research & Clinical Innovation), Birmingham, UK; Barts Heart Centre, Barts Health NHS Trust, London, UK. Electronic address:
Background: The optimal haemodynamic parameter for goal-directed resuscitation in out-of-hospital cardiac arrest (OHCA) remains uncertain. This study aimed to characterise the association between invasive blood pressure (IBP) measurements and return of spontaneous circulation (ROSC) in adult OHCA patients, to identify this parameter.
Methods: A retrospective observational study was conducted at East Anglian Air Ambulance (EAAA).
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!