Studies of lipid metabolism and peroxidation values, carried out in healthy newborns in the town of Irkutsk, have shown that total lipid and triglyceride levels in these newborns over the first ten days of their lives were similar to those in age-matched infants in the European USSR, whereas plasma total cholesterol levels were significantly higher in them as against the newborns in other regions of the country. The studies included measurements of malonic dialdehyde and total antioxidative activity of blood plasma and red cells, of catalase and peroxidase activities, of red cell peroxidation resistance.
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J Diabetes Metab Disord
June 2025
Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, P. O. Box: 1416643931, Tehran, Iran.
Objectives: An efficient approach to monitor the risks associated with chronic diseases is to use a dietary diversity score (DDS). To our knowledge, there has been no study conducted on the correlation between DDS and cardiovascular risk factors in individuals with diabetes. Hence, the objective of this study is to ascertain the correlation between these traits.
View Article and Find Full Text PDFBackground: Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by chronic hyperglycemia, mostly resulting from impaired insulin production and diminished glucose metabolism regulation. Qiwei Baizhu San (QWBZS) is a classic formula used in traditional Chinese medicine for the treatment of T2DM. A comprehensive analysis of the efficacy and safety of QWBZS in the treatment of T2DM is essential.
View Article and Find Full Text PDFFront Microbiol
January 2025
Xinjiang Key Laboratory for Ecological Adaptation and Evolution of Extreme Environment Biology, College of Life Sciences, Xinjiang Agricultural University, Ürümqi, China.
The gut microbiome was involved in a variety of physiological processes and played a key role in host environmental adaptation. However, the mechanisms of their response to altitudinal environmental changes remain unclear. In this study, we used 16S rRNA sequencing and LC-MS metabolomics to investigate the changes in the gut microbiome and metabolism of the Yarkand toad-headed agama () at different altitudes (-80 m to 2000 m).
View Article and Find Full Text PDFRedox Rep
December 2025
Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, People's Republic of China.
Objectives: Asthma, a prevalent chronic disease, poses significant health threats and burdens healthcare systems. This study focused on the role of bronchial epithelial cells in asthma pathophysiology.
Methods: Bioinformatics was used to identify key asthmarelated genes.
Se Pu
February 2025
School of Basic Medical Sciences, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Biomarkers for ischemic stroke (IS) are yet to fulfill clinical requirements. This study used non-targeted metabolomics to investigate differential metabolites and metabolic pathways in plasma and brain tissue following IS, with the aim of identifying new potential biomarkers and therapeutic targets. Twelve Tibetan miniature pigs were randomly assigned to a model- or sham-operation group.
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