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Ketogenic Diet-Associated Worsening of Osteoarthritis Histologic Secerity, Increased Pain Sensitivity and Gut Microbiome Dysbiosis in Mice.
ACR Open Rheumatol
January 2025
Oklahoma Medical Research Foundation, Arthritis & Clinical Immunology Program, the University of Oklahoma Health Sciences Center, and the Oklahoma City Veterans Affairs Medical Center.
Objectives: Dietary interventions are a potentially powerful treatment option for knee osteoarthritis (OA). The objective of this study was to evaluate a well-formulated ketogenic diet (KD) in the context of knee OA histology and pain using the destabilization of the medial meniscus (DMM) mouse model and correlate with gut microbiome and systemic cytokine levels.
Methods: Adult male mice underwent unilateral DMM or sham surgery and were then fed eight weeks of KD or chow.
Purpose: This study aimed to compare the release of the iliopsoas tendon at two levels: proximally at the pelvic brim and distally near the lesser trochanter.
Methods: The study was a randomized clinical trial. It was done to check the equivalence between two parallel groups of patients with DDH of grade 2 or more who underwent open reduction operations for their hips: Group 1, division of the iliopsoas tendon at the pelvic brim, and Group 2, division of the tendon at the lesser trochanter level.
Increased stiffness with medial column screw supplementation of lateral locking plate for distal femur fractures: a biomechanical study.
Arch Orthop Trauma Surg
January 2025
Department of Orthopaedics, Wright State University, 30 E Apple St., Suite 2200, Dayton, OH, 45409, USA.
Introduction: We propose and assess the biomechanical stability of medial column screw supplementation in a synthetic distal femur fracture model.
Materials And Methods: Twenty-four low density synthetic femora modeling osteoporotic, intraarticular distal femur fractures with medial metaphyseal comminution were split into two fixation groups: (1) lateral locking distal femur plate (PA- plate alone) and (2) lateral locking distal femur plate with a 6.5 mm fully threaded medial cannulated screw (PWS- plate with screw).
Transconjunctival correction of involutional entropion: A video demonstration.
Indian J Ophthalmol
February 2025
Department of Oculoplasty and Oncology Services (Dr. Rajendra Prasad Centre for Ophthalmic Sciences), AIIMS, New Delhi, India.
Background: Involution or aging is the most common cause of lower eyelid entropion (in-turning of eyelid margin) in the elderly population. Various pathomechanisms have been postulated for its occurrence. Aging leads to laxity of tissues and loss of muscle tone.
View Article and Find Full Text PDFMedial Patellofemoral Ligament Repair with Suture Tape Augmentation Can Yield Good Midterm Clinical Outcomes Regardless of Skeletal Maturity and Joint Laxity.
Biomimetics (Basel)
January 2025
Department of Orthopedic Surgery, Wakamatsu Hospital of University of Occupational and Environmental and Health, 1-17-1, Hamamachi, Wakamatsu, Kitakyushu-city 808-1264, Fukuoka, Japan.
While several studies have reported short-term clinical outcomes after medial patellofemoral ligament (MPFL) repair with suture tape augmentation, there is still a dearth of knowledge regarding midterm clinical outcomes. This study aimed to evaluate the midterm clinical outcomes of MPFL repair with suture tape augmentation in patients with patellar dislocation. We retrospectively reviewed the clinical records of patients who underwent MPFL repair with suture tape augmentation for at least one episode of patellar dislocation between 2015 and 2020.
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