Objective: Rapid nondestructive determination of salvianolic acid B and tanshinone IIA in Radix Salviae Miltiorrhizae with near-infrared reflectance spectroscopy.
Method: A quantitive model was built up with near-infrared diffuse reflectance spectroscopy.
Results: The RMSEP in quantitative calibration model for salvianolic acid B and tanshinone IIA were 0.259 and 0.0232 respectively.
Conclusion: NIR technique can dispose the samples without complicated pretreatment. You can achieve the results rapidly and correctly. It owns many remarkable advantages that cannot be displayed by traditional analysis methods. It is qualified to rapidly analyze traditional Chinese medicine whose components are complex. NIR can control the quality in production process of traditional Chinese medicine.
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Plant Dis
January 2025
Wenshan University, Wenshan Sanqi Institute of Science and Technology, Wenshan, Yunnan, China;
The roots of Salvia yunnanensis, an herbaceous perennial widely distributed in Southwest China, is often used as a substitute for S. miltiorrhiza, a highly valued plant in traditional Chinese medicine (Wu et al. 2014).
View Article and Find Full Text PDFCurr Issues Mol Biol
January 2025
Beijing Key Laboratory of Plant Resources Research and Development, School of Light Industry Science and Engineering, Beijing Technology and Business University, Beijing 100048, China.
Hair loss is one of the skin conditions that can affect people's mental health. Plant raw material extracts are of great interest due to their safety. In this study, we utilize reverse network pharmacology to screen for key targets of the Wnt/β-catenin signaling pathway and the TGFβ/BMP signaling pathway, as well as key differential lipids, for plant raw materials selection.
View Article and Find Full Text PDFFront Pharmacol
January 2025
School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.
Introduction: radix et rhizoma (Danshen) is a crucial medicinal material for treating cardiovascular and cerebrovascular diseases. However, the presence of adulterants and intraspecific variability poses challenges to its clinical safety.
Methods: This study collected samples of from various regions and commonly encountered adulterants.
Biofabrication
January 2025
College of Textiles & Clothing, Qingdao University, Qingdao 266071, People's Republic of China.
The design and development of advanced surgical sutures with appropriate structure and abundant bio-functions are urgently required for the chronic wound closure and treatment. In this study, an integrated technique routine combining modified electrospinning with hot stretching process was proposed and implemented to fabricate poly(L-lactic acid) (PLLA) nanofiber sutures, and the Salvia miltiorrhiza Bunge-Radix Puerariae herbal compound (SRHC) was encapsulated into PLLA nanofibers during the electrospinning process to enrich the biofunction of as-generated sutures. All the PLLA sutures loading without or with SRHC were found to exhibit bead-free and highly-aligned nanofiber structure.
View Article and Find Full Text PDFFront Pharmacol
January 2025
The Third Clinical Medical School, Guangzhou University of Chinese Medicine, Guangzhou, China.
Background: The Beclin-1/Bcl-2 complex plays a pivotal role in regulating both autophagy and apoptosis in osteoblasts affected by osteoporosis. This study first investigates whether the Bushen Jianpi Huoxue Formula can enhance the cellular function of osteoblasts. Additionally, it initially explores the functional mechanism of Beclin-1/Bcl-2-related apoptosis.
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