Purpose/objectives: To describe the notable advances in defining, conceptualizing, and measuring quality of life (QOL) in pediatric patients with cancer since the 1995 Oncology Nursing Society's State-of-the-Knowledge Conference on QOL.
Data Sources: Published research, clinical papers, and hospital policies.
Data Synthesis: QOL ratings from children and adolescents are being solicited increasingly in research and clinical assessments during treatment and survivorship using various methods but are not solicited from terminally ill patients; qualitatively induced models of pediatric cancer-related QOL now are being tested using quantitative methods.
Conclusions: Children aged five years and older are able to report their cancer-related QOL; reliable and valid QOL instruments exist for all phases of treatment except end of life.
Implications For Nursing: Nurses can involve children and adolescents in rating their QOL for research and clinical purposes and can apply theory-based QOL models to direct care.
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http://dx.doi.org/10.1188/06.ONF.S1.23-29 | DOI Listing |
Proteoglycan Res
October 2024
Department of Biochemistry and Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
Hyaluronan (HA; [-3-GlcNAc-1-beta-4-GlcA-1-beta] ), an essential matrix polysaccharide of vertebrates and the molecular camouflage coating in certain pathogens, is polymerized by "HA synthase" (HAS) enzymes. Three HAS classes have been identified with biotechnological utility, but only the Class II PmHAS from Type A has been useful for preparation of very defined HA polymers in vitro. Two general chemoenzymatic strategies with different size products are possible: (1) repetitive step-wise extension reactions by sequential addition of a single monosaccharide from a donor UDP-sugar onto an acceptor (or "primer") comprised of a short glycosaminoglycan chain (e.
View Article and Find Full Text PDFiScience
December 2024
Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, 35, Keyan Road, Zhunan Town, Miaoli County 350, Taiwan.
Shock is defined as a critical circulatory failure that requires prompt diagnosis to optimize patient outcomes. Traditional diagnostic methods have limitations, including contact-based measurements, high costs, and lengthy procedures. The study evaluated the efficacy of laser speckle contrast imaging (LSCI), a noncontact technique, for assessing peripheral hemodynamics in shock patients.
View Article and Find Full Text PDFCureus
November 2024
Physiology, All India Institute of Medical Sciences, Raebareli, Raebareli, IND.
Networking is a critical component of professional development in medical education, involving the establishment and maintenance of relationships that facilitate the exchange of information, resources, and opportunities. Defined as the process of creating and nurturing connections with peers, mentors, and collaborators, networking is essential for advancing research, enhancing career development, and improving clinical practice. This review explores the multifaceted role of networking in academia, emphasizing its importance for medical professionals who rely on collaborative efforts to drive innovation and improve patient care.
View Article and Find Full Text PDFCureus
November 2024
Department of Medicine, Baba Raghav Das Medical College, Gorakhpur, Gorakhpur, IND.
Objective: This study aimed to evaluate the severity of liver fibrosis in chronic liver disease patients using aspartate aminotransferase-to-platelet ratio index (APRI), fibrosis-4 (FIB-4), FibroScan, and the Child-Turcotte-Pugh (CTP) score. It emphasized assessing fibrosis progression toward cirrhosis (F4 stage) and exploring the correlation between non-invasive markers and the CTP score for liver function and prognosis.
Methodology: This observational cross-sectional study was conducted over one calendar year in the Department of Medicine at Baba Raghav Das (BRD) Medical College, Gorakhpur, India.
Ther Adv Med Oncol
December 2024
Department of Clinical Pharmacy, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qingchun Road, Hangzhou, Zhejiang 310003, China.
Background: A newly generic microspheres, sustained-release formulation of triptorelin acetate 3.75 mg has been developed.
Objectives: To evaluate the efficacy, pharmacokinetics, and safety of triptorelin 1-month formulation in Chinese patients with prostate cancer.
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