AI Article Synopsis
- The study examines individual differences in psychological profiles over time, building on previous research from the Berlin Aging Study.
- It identifies three distinct subgroups based on cognitive, personality, and social integration aspects, with about two-thirds of participants maintaining their subgroup classification over a six-year period.
- The findings reveal that these subgroups not only differ in well-being and mortality rates but also that movement between subgroups predicts greater declines in health and increases in mortality.
Article Abstract
Wholistic perspectives on differential change focus on multiple-indicator information at a person level. They supplement the modeling of average trajectories at a variable level. The authors extended cross-sectional work in the Berlin Aging Study (J. Smith & P. B. Baltes, 1997) to 6-year longitudinal cluster analyses (n = 132). At baseline, 3 subgroups were identified with distinct within-person psychological profiles across cognitive, personality, and social integration constructs. Over time, highly similar subgroup profiles were found, and about two thirds of the participants could be classified as remaining in the same subgroups. Baseline subgroups differed in level and slope of change and in 2 outcomes, well-being and mortality. Independent of subgroup membership, subgroup-to-subgroup change was associated with greater decline and predicted poststudy mortality. These findings demonstrate the usefulness of a wholistic approach for long-term prediction of outcomes and within-person systemic variability.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1037/0882-7974.21.4.645 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Background: Speech and language impairments are associated with cognitive decline in neurodegenerative dementias, particularly Alzheimer's Disease (AD), where subtle speech changes may precede clinical dementia onset. As clinical trials prioritize early identification for disease-modifying treatments, digital biomarkers for timely screening become imperative. Digital speech-based biomarkers can be employed for screening populations at the earliest AD stages.
View Article and Find Full Text PDFClinical Manifestations.
Alzheimers Dement
December 2024
German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Background: Previous findings evaluating longitudinal cognition in relation to the MeDi diet are inconsistent, and few studies have examined it in relation to the presence/absence of subjective cognitive decline (SCD). Our current aims are to test whether adherence to the MeDi diet is associated with the risk of clinical progression, future cognitive decline, and atrophy over time in Alzheimer's disease (AD)-sensitive regions in cognitively unimpaired (CU) older adults with or without SCD.
Methods: This longitudinal study includes 171 controls and 228 SCD patients recruited from memory clinics in the DELCODE study.
Clinical Manifestations.
Alzheimers Dement
December 2024
Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn Medical Center, Bonn, Germany.
Background: The identification of cognitively unimpaired individuals at risk of short-term cognitive decline is a critical task for Alzheimer´s disease (AD) research. Cognitively normal individuals with amyloid and/or tau pathology have a high risk for short-term cognitive decline. However, not all of these individuals show clinical progression.
View Article and Find Full Text PDFClinical Manifestations.
Alzheimers Dement
December 2024
Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Background: Sleep apnea is associated with risk of objectively-measured cognitive decline and dementia, as well as with subjective cognitive decline (SCD), itself a risk factor for cognitive decline and dementia. This relationship is understudied in ethnoracially diverse groups, however, including Latinos. This study examined associations among self-reported sleep apnea risk, SCD, and cognitive performance in community-dwelling older Latino adults.
View Article and Find Full Text PDFSingle-neuron spiking variability in hippocampus dynamically tracks sensory content during memory formation in humans.
Nat Commun
January 2025
Max Planck UCL Centre for Computational Psychiatry and Ageing Research, Max Planck Institute for Human Development, Berlin, Germany.
During memory formation, the hippocampus is presumed to represent the content of stimuli, but how it does so is unknown. Using computational modelling and human single-neuron recordings, we show that the more precisely hippocampal spiking variability tracks the composite features of each individual stimulus, the better those stimuli are later remembered. We propose that moment-to-moment spiking variability may provide a new window into how the hippocampus constructs memories from the building blocks of our sensory world.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!