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On the Effect of the Patient Table on Attenuation in Myocardial Perfusion Imaging SPECT.
EJNMMI Phys
January 2025
Institute of Radiology, Nuclear Medicine and Molecular Imaging, Heart and Diabetes Center North Rhine-Westphalia, University Hospital (Ruhr University Bochum), Medical Faculty OWL (Bielefeld University), Bad Oeynhausen, Germany.
Background: The topic of the effect of the patient table on attenuation in myocardial perfusion imaging (MPI) SPECT is gaining new relevance due to deep learning methods. Existing studies on this effect are old, rare and only consider phantom measurements, not patient studies. This study investigates the effect of the patient table on attenuation based on the difference between reconstructions of phantom scans and polar maps of patient studies.
View Article and Find Full Text PDFIntegrative single-cell and multi-omics analyses reveal ferroptosis-associated gene expression and immune microenvironment heterogeneity in gastric cancer.
Discov Oncol
January 2025
Department of General Surgery, Tianjin Fifth Central Hospital, No. 41 Zhejiang Road, Binhai New Area, Tianjin, 300450, China.
Gastric cancer (GC), a prevalent malignancy worldwide, encompasses a multitude of biological processes in its progression. Recently, ferroptosis, a novel mode of cell demise, has become a focal point in cancer research. The microenvironment of gastric cancer is composed of diverse cell populations, yet the specific gene expression profiles and their association with ferroptosis are not well understood.
View Article and Find Full Text PDFSingle-Animal, Single-Tube RNA Extraction for Comparison of Relative Transcript Levels via qRT-PCR in the Tardigrade Hypsibius exemplaris.
J Vis Exp
January 2025
Department of Molecular Cellular and Developmental Biology, University of California, Santa Barbara; Neuroscience Research Institute, University of California, Santa Barbara.
The tardigrade Hypsibius exemplaris is an emerging model organism renowned for its ability to survive environmental extremes. To explore the molecular mechanisms and genetic basis of such extremotolerance, many studies rely on RNA-sequencing (RNA-seq), which can be performed on populations ranging from large cohorts to individual animals. Reverse transcription polymerase chain reaction (RT-PCR) and RNA interference (RNAi) are subsequently used to confirm RNA-seq findings and assess the genetic requirements for candidate genes, respectively.
View Article and Find Full Text PDFEffect of ultrasonic-assisted enzymatic extraction on proso millet bran protein: extraction rate, structural and functional properties.
J Sci Food Agric
January 2025
College of Food Science and Engineering, Northwest A&F University, Yangling, China.
Background: Proso millet bran protein (PMBP), derived from agricultural by-products, possesses high nutritional value, despite its challenging extraction process. The present study proposes an extraction method for PMBP using ultrasound-assisted cellulase technology (UAE), and optimizes the process parameters. Non-waxy (N-PMBP) and waxy (W-PMBP) PMBPs, extracted through alkaline solubilization and acid precipitation (conventional treatment, CT), served as control groups to assess the impact of UAE on the structure and functionality of PMBP, as well as the distinctions between N-PMBPs and W-PMBPs.
View Article and Find Full Text PDFWhat You Need to Know About: The Management of Malignant Pleural Effusion.
Br J Hosp Med (Lond)
December 2024
Department of Respiratory Medicine, Western General Hospital, Edinburgh, UK.
Malignant pleural effusion (MPE) is a common complication of malignancy and is regularly seen on the general medicine take. Diagnosis of MPE is indicative of advanced or metastatic disease and carries a poor prognosis, with median survival ranging from 3 to 12 months. Despite recent advancements in systemic anti-cancer treatment, the goal of management in MPE remains the palliation of symptoms.
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