A 10-month-old girl was admitted with refractory infantile spasms. Video EEG demonstrated focal epileptic activity, and MRI revealed a conglomeration of annular lesions. Surgical excision was performed and pathology was consistent with tuberculoma. After antituberculous therapy, the outcome was favorable. Despite all investigations, Mycobacterium tuberculosis's mode of transmission was unclear, and both congenital and postnatal acquired forms were considered.
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http://dx.doi.org/10.1097/01.inf.0000247135.05706.e6 | DOI Listing |
Cureus
December 2024
Department of Internal Medicine, Osmania Medical College, Hyderabad, IND.
Intramedullary spinal tuberculomas constitute a small percentage of spinal tuberculosis. These, in combination with brain tuberculomas, are an uncommon manifestation of central nervous system (CNS) tuberculosis. This report details a unique case of a 32-year-old retroviral disease-positive male who presented with a two-month history of symmetrical quadriparesis and recent seizures.
View Article and Find Full Text PDFTher Adv Infect Dis
December 2024
Department of Pediatrics, All India Institute of Medical Sciences, Bathinda 151001, India.
Tuberculosis can present myriad manifestations, affecting multiple organ systems. Common central nervous system (CNS) manifestations include vomiting, headache, blurred vision, neck stiffness, altered sensorium, seizures, and focal neurological deficits. Epilepsia partialis continua (EPC) is a rare manifestation of CNS tuberculosis.
View Article and Find Full Text PDFActa Neurochir Suppl
November 2024
Section of Neurosurgery, Department of Neurological Sciences, Christian Medical College Hospital, Vellore, Tamil Nadu, India.
A 39-year-old man received empiric treatment for pulmonary tuberculosis (TB). After developing sensory seizures he was restarted on anti-TB drugs when a brain MRI showed a 4.3 cm left parietal enhancing lesion with extensive edema.
View Article and Find Full Text PDFSurg Neurol Int
October 2024
Hassan 2 University, Faculty of Medicine and Pharmacy, Casablanca, Morocco.
Background: Giant intracranial tuberculomas are rare space-occupying lesions in the brain parenchyma, with a diameter >2.5 cm. They can mimic gliomas, meningiomas, and metastases.
View Article and Find Full Text PDFBMJ Case Rep
November 2024
Pediatrics, AIIMS Raipur, Raipur, Chhattisgardh, India
Tuberculosis is a global disease and presents with an array of neurological manifestations. Presentation varies from meningitis, radiculo-myelitis, tuberculoma, brain abscess and other combinations. The association of Guillain-Barre' syndrome (GBS) with tuberculosis has been reported in a few reports.
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