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Alzheimers Dement
December 2024
Division of Geriatrics, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Background: The omega-3 fatty acid eicosapentaenoic acid (EPA) has positive benefits for cardiovascular risk, reducing inflammation and improving endothelial function. Evidence suggests that Icosapent ethyl, a purified form of EPA, can improve cardiovascular outcomes in at-risk patients. Veterans are at higher risk for vascular dysfunction, a risk factor of Alzheimer's disease (AD), thus improving vascular health may be pivotal for delaying or preventing AD among Veterans.
View Article and Find Full Text PDFErythrocyte Membrane Fluidity and Omega-3 Fatty Acid Intake: Current Outlook and Perspectives for a Novel, Nutritionally Modifiable Cardiovascular Risk Factor.
Nutrients
December 2024
Endocrinologia e Diabetologia, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00136 Rome, Italy.
Omega-3 fatty acids reduce triglycerides and have several positive effects on different organs and systems. They are also found in the plasma membrane in variable amounts in relation to genetics and diet. However, it is still unclear whether omega-3 supplementation can reduce the occurrence of major cardiovascular events (MACEs).
View Article and Find Full Text PDFDietary Eicosapentaenoic Acid Improves Ozone-Induced Pulmonary Inflammation in C57BL/6 Mice.
J Nutr
November 2024
Division of Pulmonary, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States. Electronic address:
Background: Ambient concentrations of the air pollutant, ozone, are rising with increasing global temperatures. Ozone is known to increase incidence and exacerbation of chronic lung diseases, which will increase as ambient ozone levels rise. Studies have identified diet as a variable that is able to modulate the pulmonary health effects associated with ozone exposure.
View Article and Find Full Text PDFLipoxygenase activity in tropical fish: Changes during surimi processing and some biochemical characterization in lizardfish (Saurida tumbil).
J Food Sci
December 2024
School of Food Technology, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima, Thailand.
The lipoxygenase (LOX) activity of major tropical fish used for surimi production, including threadfin bream (TB), lizardfish (LZ), and goatfish (GF), was measured in the gills, skin, and muscle. The highest LOX activity was observed in the LZ samples (p < 0.05), with the gills exhibiting the greatest activity at 376.
View Article and Find Full Text PDFBeyond LDL-C: unravelling the residual atherosclerotic cardiovascular disease risk landscape-focus on hypertriglyceridaemia.
Front Cardiovasc Med
August 2024
Faculty of Biology Medicine and Health, University of Manchester, Manchester, United Kingdom.
Article Synopsis
- Atherosclerotic cardiovascular disease (ASCVD) risk has traditionally focused on lowering LDL cholesterol, but this review highlights the significance of hypertriglyceridaemia as another critical risk factor.
- Despite treating patients with LDL-lowering therapies, high triglyceride levels continue to pose a risk for ASCVD, especially when paired with low HDL cholesterol levels.
- Recent studies show mixed results regarding triglyceride-lowering medications, with purified eicosapentaenoic acid (EPA) showing promise, suggesting the need for updated clinical guidelines and further investigation into novel therapies targeting other ASCVD risk factors.
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