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Respiratory support strategies in neonatal transport in the UK and Ireland.
Eur J Pediatr
January 2025
Department of Women and Children's Health, School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, Denmark Hill, London, UK.
Unlabelled: Infants requiring interhospital transfer for a higher level of care in the neonatal period are at increased risk of adverse outcomes. Optimising respiratory management is an important priority. The aim of this survey was to investigate current respiratory support strategies in neonatal transport and identify opportunities for the optimisation of clinical care and future research.
View Article and Find Full Text PDFAssociations of intraoperative end-tidal CO levels with postoperative outcome-secondary analysis of a worldwide observational study.
J Clin Anesth
December 2024
Department of Anaesthesiology, Amsterdam University Medical Centers, Amsterdam, The Netherlands; Department of Anaesthesiology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
Background: Patients receiving intraoperative ventilation during general anesthesia often have low end-tidal CO (etCO). We examined the association of intraoperative etCO levels with the occurrence of postoperative pulmonary complications (PPCs) in a conveniently-sized international, prospective study named 'Local ASsessment of Ventilatory management during General Anesthesia for Surgery' (LAS VEGAS).
Methods: Patients at high risk of PPCs were categorized as 'low etCO' or 'normal to high etCO' patients, using a cut-off of 35 mmHg.
Optimal Maternal Ventilation During Laparotomy with General Anesthesia in Pregnancy in the Ovine Model.
Anesth Analg
January 2025
From the Department of Anesthesiology, UZ Leuven, Leuven, Belgium.
Background: General anesthesia during pregnancy is not uncommon, for example, for trauma surgery, cerclage, or cesarean delivery. Current recommendations are to maintain maternal partial pressure of carbon dioxide in arterial blood (paCO2) at 30 mm Hg, which is based solely on the average maternal paCO2 in awake pregnant women. However, there is no evidence that this target, compared to other targets, would enable optimal conditions for the fetus during general anesthesia.
View Article and Find Full Text PDFThe impact of gasping versus apnea on initial heart rate and response to positive pressure ventilation in the delivery room following interruption of placental blood flow.
Resuscitation
December 2024
Department of Pediatrics, POB 8100 4068, Stavanger, Norway, Stavanger University Hospital and University of Stavanger; Department of Anaesthesiology & Intensive Care, Stavanger University Hospital, POB 8100 4068, Stavanger, Norway. Electronic address:
Background: The impact and/or significance of gasping or apnea on cardio-respiratory status at birth remains unclear.
Objectives: The study objectives were to determine in infants presenting with gasping or apnea in the delivery room, initial heart rate (HR), responses to positive pressure ventilation (PPV), time to onset of spontaneous respirations, and the relationship of these responses to 24-hour outcome (death/survival) METHODS: Observation study undertaken in a rural setting involving late preterm and term newborns who gasped (n=126) or were apneic (n=105) at birth and received PPV had HR and respiratory parameters continuously measured and were video recorded.
Results: Apneic (12.
Left of sternum compressions are associated with higher systolic blood pressure than lower half of sternum compressions in cardiac arrest.
Resuscitation
December 2024
Northwell, New Hyde Park, New York, United States; Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, United States.
Introduction: Limited evidence supports guidelines to perform chest compressions at the lower half of the sternum. Imaging studies suggest this location may obstruct blood flow. Our primary aim was to compare the highest arterial line systolic blood pressure (SBP) during lower-half-of-sternum chest compressions (CC) versus those left-of-sternum, where the left ventricle is more likely located.
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