Examination of trained (43 skiers) and untrained senior schoolchildren (31 young males); low-order students-skiers (110 girls) and untrained students (17 girls); high-order students-skiers (n=39) and students not going in for sports (n=60) established that in school children and female students of both groups, the cellular and humoral immunogical changes were mainly seasonal: in spring versus autumn, a considerable reduction in the concentration of immunoglobulins (Ig) G, M, and A and circulating immune complexes (CIC) was attended by a significant B-immunity system increase. In the high-order skiers, the time course of changes in immunological responsiveness depended on both a season and a muscle activity regime. In autumn with the start of intensive training loads, the vast majority of immune defense parameters (9/12) were significantly higher in the trained skiers than in the untrained. In spring versus autumn, despite a significant reduction in many cellular and humoral immunological parameters with a considerable increase in the count of T and B lymphocytes in both groups of students, many parameters, in particular the levels of T and B lymphocytes, IgG, and CIC usually remained higher in the sporting students than those in the untrained students of the same age.

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