AI Article Synopsis
- Recent research in neuroprosthetics has mainly focused on the motor cortex, but conditions like ALS can damage this area, limiting its use.
- This study explores the potential of the cingulate cortex as an alternative source for voluntary control in neuroprosthetics.
- Experiments showed that rats could effectively control spiking activity in the cingulate cortex for rewards, indicating its flexibility and usefulness for neuroprosthetic applications.
Article Abstract
Recent neuroprosthetic work has focused on the motor cortex as a source of voluntary control signals. However, the motor cortex can be damaged in upper motor neuron degenerative diseases such as primary lateral sclerosis and amyotrophic lateral sclerosis. The possibility exists that prefrontal areas may also be used in neuroprosthetic devices. Here, we report the use of the cingulate cortex in a neuroprosthetic model. Seven rats were able to significantly modulate spiking activity in the cingulate cortex in order to receive reward. Furthermore, experiments with single neurons provide evidence that the cingulate cortex neuronal modulation is highly flexible and thus useful for a neuroprosthetic device.
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| http://dx.doi.org/10.1109/TNSRE.2006.886730 | DOI Listing |
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