The technique of atmospheric pressure photoionization (APPI) has several advantages over electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI), including efficient ionization of nonpolar or low charge affinity compounds, reduced susceptibility to ion suppression, high sensitivity, and large linear dynamic range. These benefits are greatest at low flow rates (i.e.,
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709839 PMC http://dx.doi.org/10.1016/j.jasms.2006.11.004 DOI Listing Publication Analysis
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